Results 221 to 230 of about 3,406,662 (333)

Associations between metal exposure and metabolic syndrome: exploring the mediating role of biological ageing among US adults. [PDF]

Diabetol Metab Syndr
Zheng L, Lu X, Luo S, Guo J, Xu X, Yang L, Chen M, Lin S, Xie X, Li H, Wu S.   +10 more
europepmc   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Accelerated biological ageing in familial pulmonary fibrosis. [PDF]

Eur Respir J
Serezani APM, Mitchell DB, Cogan JD, Malabanan MMU, Markin CR, Garnett ET, Fadely TH, Kropski JA, Salisbury ML, Blackwell TS.   +9 more
europepmc   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Joint association between physical exercise, caffeine intake, and biological ageing: A cross-sectional analysis of population-based study. [PDF]

PLoS One
Chen G, Zhou S, Xun Y, Fong TL, Tang G, Wang J, Li H, Yin X, Gao J, Zhu G, Wu Y, Li J, Sun YX, Li Y, Zhou J, Feng Y.   +15 more
europepmc   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Ultra-processed foods, biological ageing, and all-cause mortality risk: a prospective cohort study using 172,225 participants from UK Biobank. [PDF]

Geroscience
Wang Y, Qi T, Wu X, Li C, Zeng B, Huang P, Liu D, Liang S, Yang F, Xu F, Su C, Zhang B, Dai J.   +12 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

A prospective cohort study to develop multi-biomarkers panel to define biological ageing in six different cohorts from newborn to oldest adult: a study protocol. [PDF]

Biol Methods Protoc
Chatterjee P, Jain R, Attri P, Chakrawarty A, Rani L, Dey S, Pradhan R, Kulshrestha V, Ramakrishnan L.   +8 more
europepmc   +1 more source