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HPTLC assay of nicotine and cotinine in biological samples [PDF]

open access: diamondJournal of Mind and Medical Sciences, 2018
This study presents the development of a simple high-performance thin layer chromatography (HPTLC) method for the determination of nicotine and its metabolite cotinine in human plasma and urine. The following mobile phases: methanol: ammonia (100:1.5, v:
Ana Maria Vlasceanu   +6 more
doaj   +4 more sources

A weakly supervised framework for automated biological assay assessment [PDF]

open access: yesVirus Research
The quantification of biological assays, such as plaque and microbial assays is essential in virology and microbiology research. However, low-contrast images of stain-free samples are difficult to segment accurately and manual labeling is time-consuming.
Hongru Jiang   +4 more
doaj   +2 more sources

Microemulsion based on methyl 3,4,5-trihydroxybenzoate for the topical treatment of cutaneous leishmaniasis: an in vivo assay [PDF]

open access: yesActa Amazonica, 2023
Cutaneous leishmaniasis, caused by protozoa of the genus Leishmania, presents diverse clinical manifestations, and current therapeutic options have limitations, including long treatment periods, potential hospitalization, and excessive pain during ...
Thiago de Jesus BACHA   +8 more
doaj   +1 more source

Hydrophobic mismatch and sequence specificity compete when transmembrane helix-helix interactions are measured with the TOXCAT assay

open access: yesFrontiers in Chemistry, 2022
Genetic assays capable of measuring the propensity of transmembrane helices to oligomerize within the cytoplasmic membrane of the bacterium E. coli are frequently used when sequence-specificity in transmembrane helix-helix interactions is investigated ...
Nadja Hellmann   +2 more
doaj   +1 more source

AutoPlate: Rapid Dose-Response Curve Analysis for Biological Assays

open access: yesFrontiers in Immunology, 2022
The emergence of COVID-19 has emphasised that biological assay data must be analysed quickly to develop safe, effective and timely vaccines/therapeutics.
Phil Palmer   +9 more
doaj   +1 more source

Understanding the Role of Surface Modification of Randomized Trabecular Titanium Structures in Bone Tissue Regeneration: An Experimental Study

open access: yesMedicina, 2022
Background and Objectives: Three-dimensional (3D) metallic trabecular structures made by additive manufacturing (AM) technologies promote new bone formation and osteointegration.
Elena Canciani   +8 more
doaj   +1 more source

Characterization of Prunus Necrotic Ringspot Virus and Cherry Virus A Infecting Myrobalan Rootstock

open access: yesViruses, 2023
Prunus necrotic ringspot virus (PNRSV) and cherry virus A (CVA) are two viruses that mainly infect plants of the genus Prunus. Full-length sequences of these two viruses, collected in the Czech Republic from Prunus cerasifera plants, were obtained via ...
Karima Ben Mansour   +3 more
doaj   +1 more source

Design, Synthesis, Fungicidal and Insecticidal Activities of Novel Diamide Compounds Combining Pyrazolyl and Polyfluoro-Substituted Phenyl into Alanine or 2-Aminobutyric Acid Skeletons

open access: yesMolecules, 2023
Thirty novel diamide compounds combining pyrazolyl and polyfluoro-substituted phenyl groups into alanine or 2-aminobutyric acid skeletons were designed and synthesized with pyflubumide as the lead compound to develop potent and environmentally friendly ...
Zhi-Yuan Xu   +7 more
doaj   +1 more source

Biological and physico-mechanical properties of poly(methyl methacrylate) enriched with graphene oxide as a potential biomaterial

open access: yesJournal of Oral Research, 2021
Objective: To determine the cytotoxicity and effects of graphene oxide (GO) on cellular proliferation of gingival-fibroblasts, pulpdental cells and human osteoblasts in culture, and to determine the physical, mechanical and biological properties of poly (
René García-Contreras   +3 more
doaj   +1 more source

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