Results 221 to 230 of about 2,148,890 (355)

An extensive direct assay in biological assay

An extensive direct assay in biological assay
The ordinary method of the biological direct assay has been described by many authors and most investigators being engaged in the biological assay have practiced the method for a long time. It seems, however, to us that the method is in need of large number of subjects and the fiducial limits appling Fieller's theorem are mostly too wide to be useful ...
openaire  

Multiplex Real-Time PCR Assay Using TaqMan Probes for the Identification of Trypanosoma cruzi DTUs in Biological and Clinical Samples

, 2015
Carolina Cura, Tomás Duffy, Raúl Horacio Lucero, Margarita Bisio, Julie Péneau, Matilde Jiménez‐Coello, Eva Muñoz, María-José Giménez, Edward Valencia Ayala, Sonia A. Kjos, José Santalla, Susan M. Mahaney, Nelly M. Cayo, Claudia Nagel, Laura Barcán, Edith Málaga, Karla Y. Acosta-Viana, Laurent Brutus, Susana Blanca Ocampo, Christine Aznar, César Augusto Cuba Cuba, Ricardo E. Gürtler, Janine M. Ramsey, Isabela Ribeiro, John L. VandeBerg, Zaida E. Yadón, Antonio Osuna, Alejandro G. Schijman   +27 more
openalex   +2 more sources

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Supplementary material to "Twin-plate ice nucleation assay (TINA) with infrared detection for high-throughput droplet freezing experiments with biological ice nuclei in laboratory and field samples"

, 2018
Anna T. Kunert, Mark Lamneck, Frank Helleis, Mira L. Pöhlker, Ulrich Pöschl, Janine Fröhlich‐Nowoisky   +5 more
openalex   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Correction: Bioproduction, characterization, anticancer and antioxidant activities of extracellular melanin pigment produced by newly isolated microbial cell factories Streptomyces glaucescens NEAE-H. [PDF]

Sci Rep
El-Naggar NE, El-Ewasy SM.
europepmc   +1 more source

The Biological Assay of Rhubarb

, 1974
Makoto Tsukui, MINORU YAMAZAKI, TOMOYOSHI TOYOSATO, Toshiro Matsuoka, Hajimè Fujimura   +4 more
openalex   +2 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Evaluation of the Idylla IDH1-2 Mutation Assay for the Detection of <i>IDH</i> Variants in Solid Tumors and Hematological Malignancies. [PDF]

Int J Mol Sci
Gilson P, Muller M, Gauchotte G, Fadil S, Husson M, Hanriot I, Witz A, Dardare J, Betz M, Merlin JL, Harlé A.   +10 more
europepmc   +1 more source

Integrating Molecular Networking and Biological Assays To Target the Isolation of a Cytotoxic Cyclic Octapeptide, Samoamide A, from an American Samoan Marine Cyanobacterium

, 2017
C. Benjamin Naman, Ramandeep Rattan, Svetlana E. Nikoulina, J. Jack Lee, Bailey W. Miller, Nathan A. Moss, Lorene Armstrong, Paul D. Boudreau, Hosana Maria Debonsi, Frederick A. Valeriote, Pieter C. Dorrestein, William H. Gerwick   +11 more
openalex   +1 more source