Results 251 to 260 of about 4,550,163 (310)

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

The spiral evolution of techniques for the laboratory diagnosis of microbial infections. [PDF]

Front Cell Infect Microbiol
Tang YW, Ismail N, García-Contreras R.
europepmc   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Autophagy inhibition sensitizes radiotherapy responses in high-grade mutant IDH1 glioma. [PDF]

Nat Commun
Núñez FJ, Banerjee K, Mujeeb AA, Mauser A, Tronrud CE, Zhu Z, Raghuram S, Sheth MR, Pena Agudelo JA, Zelaya J, Taher A, Kadiyala P, Carney SV, Garcia-Fabiani MB, Comba A, Alghamri MS, McClellan BL, Klaiss A, Nwosu ZC, Hong HS, Sajjakulnukit P, Qin T, Sartor MA, Ljungman M, Welch JD, Cheng SY, Lowenstein PR, Lahann J, Lyssiotis CA, Castro MG.   +29 more
europepmc   +1 more source

Light-responsive PyNAC90 orchestrates anthocyanin biosynthesis through combinatorial transcriptional activation and COP1-mediated degradation in pear. [PDF]

Mol Hortic
Han C, Xue Z, Chen G, Shan Y, Yao C, Zhao Y, Li B, Miao Y, Zeng J, Wang T, Yang G, Wu J.   +11 more
europepmc   +1 more source

Serum from Patients with Antiphospholipid Syndrome Differentially Affects Venous and Microcirculatory Endothelial Cells. [PDF]

Biology (Basel)
Mancardi D, Shelton Agar FMA, Pagliaro P, Marinotti C, Arrigo E, Barinotti A, Cecchi I, Radin M, Foddai SG, Roccatello D, Sciascia S.   +10 more
europepmc   +1 more source

Surface display of co-stimulatory ligand B7H2 on engineered bacteria enhances tumor immunotherapy. [PDF]

Cell Rep Med
Feng Q, Wang C, Li Z, Sheng D, Shi S, Liu J, Chen B.   +6 more
europepmc   +1 more source

Direct activation of SARM1 by dsDNA is not supported by biochemical and cellular evidence. [PDF]

Proc Natl Acad Sci U S A
Kao AH, Mishra BP, Sorbello M, Zhang W, Zhou Q, Jiang Y, Masic V, Harten P, Gu W, Yang JY, Bloom AJ, Mitra RD, Zhang Z, Zhao YJ, Orsomando G, Wang X, Milbrandt J, Kobe B, Ve T, DiAntonio A.   +19 more
europepmc   +1 more source

Cytotoxic Effects of Flowable Composite Resins with Different Resin Matrix Compositions on L929 Fibroblasts. [PDF]

Oral Health Prev Dent
Yazıcı Akbıyık S, Yikici Col C, Kilic S, Kacaroglu D.   +3 more
europepmc   +1 more source

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Biological assay

2021
Praveen Rai, Surendra Nimesh
exaly   +2 more sources