Results 291 to 300 of about 2,148,890 (355)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Infectious, Allergic, and Immune-Mediated Disease Data Resources: a Landscape Overview and Subset Assessment. [PDF]

J Med Syst
Pokutnaya D, Mayer LM, Foote S, Hartwick M, Mazrouee S, Van Panhuis WG, Shabman R.   +6 more
europepmc   +1 more source

Hsa_circ_0000437 promotes the progression of rheumatic valvular heart disease by activating the mitogen-activated protein kinase signaling pathways after sponging let-7f-5p and targeting RAS-like proto-oncogene B. [PDF]

Hum Cell
Zhu L, Li N, Shi H, Song J, Fang Z, Shen Q, Zhu X, Dan Y, Shao G, Sun L.   +9 more
europepmc   +1 more source

Investigating the role of cytochrome <i>bd</i> oxidases in the antibacterial activity of madecassic acid and derivatives thereof. [PDF]

RSC Med Chem
Henry SA, Sansom GN, Tran TTP, Boughton RA, Joiner G, Webster CM, de Silva HIC, Garrett MD, Serpell CJ, Robinson GK, Shepherd M.   +10 more
europepmc   +1 more source

Ph Sensitive Magnetic Graphene Oxide Microbeads for Drug Delivery Systems and Biological Assays

Seyma Sari, Muharrem Karabörk, Sabahattin Cömertpay   +2 more
openalex   +1 more source

Plant rhabdovirus glycoprotein activates unfolded protein response-mediated antiviral ER-phagy in insect vectors. [PDF]

PLoS Pathog
Chen S, Cheng Y, Tang Y, Zhang J, Li Y, Jia D, Chen H, Wei T.   +7 more
europepmc   +1 more source

Biological activity of recombinant accessory cholerae enterotoxin (ace) on rabbit ileal loops and antibacterial assay.

, 2012
Shaghayegh Anvari, Shahin Najar Peerayeh, Mehrdad Behmanesh, Mina Boustanshenas   +3 more
openalex   +1 more source

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Biological Assays

2017
The biological ...
Rowhani A, La Notte P, Uyemoto J K, Daubert S D, Savino V   +4 more
openaire   +3 more sources