Results 131 to 140 of about 9,490,238 (346)

Annual Report - Marine Biological Laboratory, 1942

, 1943
Annual report of the Marine Biological Laboratory in Woods Hole. 1942.
Marine Biological Laboratory (Woods Hole MA)
core  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Molecular characterization of Cryphonectria parasitica isolates from Basilicata region (Southern Italy) and mycovirus identification

Journal of Biological Research
Chestnut is a valuable species that grows widely throughout the Italian peninsula. It is susceptible to different diseases and among them chestnut blight caused by Cryphonectria parasitica is the most devastating one.
Stefania Mirela Mang, Carmine Marcone, Maria Marcone, Giuseppe Malvasi, Danut Chira, Florentina Chira, Aurel Maxim, Ippolito Camele   +7 more
doaj   +1 more source

Discovery of Guanfacine as a Novel TAAR1 Agonist: A Combination Strategy through Molecular Modeling Studies and Biological Assays. [PDF]

Pharmaceuticals (Basel), 2023
Cichero E, Francesconi V, Casini B, Casale M, Kanov E, Gerasimov AS, Sukhanov I, Savchenko A, Espinoza S, Gainetdinov RR, Tonelli M.   +10 more
europepmc   +1 more source

Annual Report - Marine Biological Laboratory, 1894

, 1895
Annual report of the Marine Biological Laboratory in Woods Hole. 1894.
Marine Biological Laboratory (Woods Hole MA)
core  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Evaluation of a serological reference panel for Lassa virus

International Journal of Infectious Diseases, 2020
E. Bentley, S. Richardson, M. Killip, M. Hassall, R. Garry, V. Bernasconi, J. Holst, M. Page, G. Mattiuzzo   +8 more
doaj   +1 more source

Curcumin-loaded mesoporous silica nanoparticles for drug delivery: synthesis, biological assays and therapeutic potential - a review. [PDF]

RSC Adv, 2023
Iranshahy M, Hanafi-Bojd MY, Aghili SH, Iranshahi M, Nabavi SM, Saberi S, Filosa R, Nezhad IF, Hasanpour M.   +8 more
europepmc   +1 more source

Annual Report - Marine Biological Laboratory, 1934

, 1935
Annual report of the Marine Biological Laboratory in Woods Hole. 1934.
Marine Biological Laboratory (Woods Hole MA)
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source