Results 131 to 140 of about 168 (163)
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Journal of the American Pharmaceutical Association (Scientific ed.), 1949
It has been found that rodents are suitable test animals (or use in determining the potency of senna, and in the present work mice were used. The assay procedure described involves administering the preparation under test at three dosage levels selected with a view to producing positive laxative effects in approximately 25, 50, and 75 of three similar ...
L C, MILLER, E B, ALEXANDER
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It has been found that rodents are suitable test animals (or use in determining the potency of senna, and in the present work mice were used. The assay procedure described involves administering the preparation under test at three dosage levels selected with a view to producing positive laxative effects in approximately 25, 50, and 75 of three similar ...
L C, MILLER, E B, ALEXANDER
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A BIOLOGICAL ASSAY FOR CALCITONIN
Journal of Endocrinology, 1965SUMMARY (1) Calcitonin preparations from acetone-dried thyroid were administered to rats by various routes. (2) Intravenous administration, especially by infusion, produced a much greater fall in plasma calcium than s.c. or i.p. injection. (3) The log dose-effect curves after i.v.
M A, Kumar +6 more
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Biological assays for interferons
Journal of Immunological Methods, 2002Interferons (IFN) are potent biologically active proteins synthesised and secreted by somatic cells of all mammalian species. They have been well characterised, especially those of human origin, with respect to structure, biological activities, and clinical therapeutic effects.
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The Biological Assay of Diphtherial Toxoid
The Journal of Immunology, 1948Summary Three methods for the biological assay of diphtherial toxoid have been presented. Due to economy of animals and other practical considerations, the method involving the skin test as the challenging dose has been selected as the method of choice. Prigge’s observations on the value of Lf determinations have been discussed.
L, GREENBERG, M, ROBLIN
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Biologic Assay of Mercury Ointments*†
Journal of the American Pharmaceutical Association (Scientific ed.), 1947Using the storage of mercury in the kidney of the rat as a measure of cutaneous penetration, 8 official mercury ointments have been assayed. Mercury oleate and nitrate ointments showed the greatest penetration; calomel and yellow mercuric oxide showed the least.
E P, LAUG, E A, VOS, F M, KUNZE
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A Sensitive Biologic Assay for ACTH
Endocrinology, 1962Fluorometric determination of corticosteroids in adrenal venous plasma of the acutely hypophysectomized rat has led to the development of 2 new techniques for the measurement of ACTH. The first, consisting of jugular injection of test material, with adrenal venous bleeding 5 minutes later, gives linearity of response to log doses of ACTH ranging from 0.
H S, LIPSCOMB, D H, NELSON
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A sensitive biological assay for interferons
Journal of Immunological Methods, 1995Several assays are available for interferons that either measure activity (bioassays) or protein mass (ELISAs). Bioassays generally require the use of viruses and some means of determining cell killing. Many investigators lack the expertise to work with potentially harmful viral agents and eschew this approach in favor of an ELISA assay based on a ...
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Assay of hypoglycin in biological samples
Analytical Biochemistry, 1978Abstract A simple and rapid colorimetric method, applicable to extracts of biological samples, is reported for measuring the toxic amino acid l -α-amino-β-methylenecyclopropylpropionic acid (hypoglycin). By fluorimetry, as little as 10 nmol (0.14 μg) can be assayed.
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Assay of hydroxyfarrerol in biological fluids
Journal of Chromatography A, 1990A high-performance liquid chromatographic method for the determination of hydroxyfarrerol (IdB 1031) in biological samples was developed. IdB 1031 was first extracted by liquid-solid partition and the extracts were evaporated and analysed on a reversed-phase column under isocratic conditions, using either an electrochemical or a UV detector.
A, Marzo +4 more
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