Results 161 to 170 of about 9,490,238 (346)

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Corrigendum: Chimeric design, synthesis, and biological assays of a new nonpeptide insulin-mimetic vanadium compound to inhibit protein tyrosine phosphatase 1B

Drug Design, Development and Therapy, 2010
Error in author listDr Melendez was incorrectly affiliated in "Chimeric design, synthesis, and biological assays of a new nonpeptide insulinmimetic vanadium compound to inhibit protein tyrosine phosphatase 1B", published in Drug Design,
Scior T, Guevara-Garcia JA, Melendez FJ, et al   +3 more
doaj  

Development of a high-performance thin-layer chromatography (HPTLC) method coupled with chemometric fingerprinting analysis for rapid identification and quantification of soyasaponins

Frontiers in Natural Products
IntroductionSaponins, produced by plants, are tensioactives secondary metabolites. Those molecules provide emulsifying and stabilizing properties that have been exploited in the pharmaceutical and food industries.
Génesis Chavarría-Montero, Angélica Sibaja-Salazar, Sergio Nates, Víctor Álvarez-Valverde, Pablo Jiménez-Bonilla, Pablo Jiménez-Bonilla   +5 more
doaj   +1 more source

Discovery of Chitin Deacetylase Inhibitors through Structure-Based Virtual Screening and Biological Assays. [PDF]

J Microbiol Biotechnol, 2022
Liu Y, Ahmed S, Fang Y, Chen M, An J, Yang G, Hou X, Lu J, Ye Q, Zhu R, Liu Q, Liu S.   +11 more
europepmc   +1 more source

Annual Report - Marine Biological Laboratory, 1890

, 1890
Annual report of the Marine Biological Laboratory in Woods Hole. 1890.
Marine Biological Laboratory (Woods Hole MA)
core  

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Discovery of new pyridine heterocyclic hybrids; design, synthesis, dynamic simulations, and in vitro and in vivo breast cancer biological assays. [PDF]

RSC Adv, 2023
Abdelshaheed MM, El Subbagh HI, Tantawy MA, Attia RT, Youssef KM, Fawzy IM.   +5 more
europepmc   +1 more source

Annual Report - Marine Biological Laboratory, 1903-1906

, 1907
https://hdl.handle.net/1912/21944Marine Biological Laboratory.
Marine Biological Laboratory (Woods Hole MA)
core  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Annual Report - Marine Biological Laboratory, 1909

, 1910
Annual report of the Marine Biological Laboratory in Woods Hole. 1909.
Marine Biological Laboratory (Woods Hole MA)
core