Results 181 to 190 of about 3,956,990 (303)

Annual Report - Marine Biological Laboratory, 1967

, 1968
Annual report of the Marine Biological Laboratory in Woods Hole. 1967.
Marine Biological Laboratory (Woods Hole MA)
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

FibroPrep protocol for rapid enzyme-free isolation of primary dermal fibroblasts from adult mouse skin for biological assays. [PDF]

STAR Protoc
Chakraborty S, Pradhan S, Srinivasan D, Mukherjee B.   +3 more
europepmc   +1 more source

Microfluidic Systems with Embedded Cell Culture Chambers for High-Throughput Biological Assays. [PDF]

ACS Appl Bio Mater, 2020
Jaberi A, Monemian Esfahani A, Aghabaglou F, Park JS, Ndao S, Tamayol A, Yang R.   +6 more
europepmc   +1 more source

Annual Report - Marine Biological Laboratory, 1926

, 1927
Annual report of the Marine Biological Laboratory in Woods Hole. 1926.
Marine Biological Laboratory (Woods Hole MA)
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

PEGASUS: Unlocking Polarity in Cell-Permeable Cyclic Peptides Using AI Models Built on Massively Parallel Biological Assays. [PDF]

J Med Chem
Baker C, Acquah FA, Chivukula LG, Wu L, Philippe-Venec L, Abedi M, Tao Y, Ramírez D, McCoy MD, Moore B, Asher JO.   +10 more
europepmc   +1 more source

Small molecular adjuvants repurpose antibiotics towards Gram-negative bacterial infections and multispecies bacterial biofilms. [PDF]

Chem Sci, 2023
Dey R, Mukherjee S, Mukherjee R, Haldar J.   +3 more
europepmc   +1 more source

Annual Report - Marine Biological Laboratory, 1948

, 1948
Annual report of the Marine Biological Laboratory in Woods Hole. 1948.
Marine Biological Laboratory (Woods Hole MA)
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source