Results 221 to 230 of about 6,386,574 (334)

Discovery of Novel Thiazole-Based SIRT2 Inhibitors as Anticancer Agents: Molecular Modeling, Chemical Synthesis and Biological Assays. [PDF]

open access: yesInt J Mol Sci
Piacente F   +11 more
europepmc   +1 more source

Human bone morphogenetic protein-2 (hBMP-2) characterization by physical-chemical, immunological and biological assays. [PDF]

open access: yesAMB Express, 2020
Suzuki MF   +11 more
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Integration of In Vitro and In Silico Results From Chemical and Biological Assays of <i>Rheum turkestanicum</i> and <i>Calendula officinalis</i> Flower Extracts. [PDF]

open access: yesFood Sci Nutr
Korpayev S   +10 more
europepmc   +1 more source

Preparation of glass-ionomer cement containing ethanolic Brazilian pepper extract (Schinus terebinthifolius Raddi) fruits: chemical and biological assays. [PDF]

open access: yesSci Rep, 2020
Pinto IC   +12 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Ligand-Based Virtual Screening for Discovery of Indole Derivatives as Potent DNA Gyrase ATPase Inhibitors Active against Mycobacterium tuberculosis and Hit Validation by Biological Assays. [PDF]

open access: yesJ Chem Inf Model
Pakamwong B   +18 more
europepmc   +1 more source

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