Results 111 to 120 of about 2,832,681 (326)

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Агрономическа пригодност на земите от района на град Велинград за отглеждане на хмел

open access: yesПочвознание, агрохимия и екология, 2012
A brief botanical characteristic and survey of agroecological requirements of the hop plants was presented. Climatic conditions and soil resources in the region of Velingrad were considered.
ИВАНКА ЛЮБЕНОВА   +1 more
doaj  

Effects of biological agents on rhizosphere microecological environment and nutrient availability for rice

open access: yesFrontiers in Microbiology
As the world’s population grows, pursuing sustainable agricultural production techniques to increase crop yields is critical to ensuring global food security.
Hang Zhou   +14 more
doaj   +1 more source

A Simple and Rapid Method to Evaluate Potentially Mineralizable Nitrogen in Sewage Sludge Amended Calcareous Soils [PDF]

open access: yesآب و فاضلاب, 2005
Potentially mineralizable nitrogen (PMN) can be usually considered as labile nitrogen. Measurement of PMN is expensive and time consuming; therefore, a simpler and more rapid alternative may facilitate routine laboratory analysis.
Yazdan Lotfi   +2 more
doaj  

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

An orally available small molecule that targets soluble TNF to deliver anti-TNF biologic-like efficacy in rheumatoid arthritis

open access: gold, 2022
Alexander Vugler   +25 more
openalex   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

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