Results 121 to 130 of about 1,629,666 (196)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Correction: Plant factories are heating up: hunting for the best combination of light intensity, air temperature and root-zone temperature in lettuce production. [PDF]

Front Plant Sci
Carotti L, Graamans L, Puksic F, Butturini M, Meinen E, Heuvelink E, Stanghellini C.   +6 more
europepmc   +1 more source

[Biological availability of drugs].

Farmatsevtychnyi zhurnal, 1979
openaire   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Fungal Endophyte Comprehensively Orchestrates Nodulation and Nitrogen Utilization of Legume Crop (Arachis hypogaea L.). [PDF]

J Fungi (Basel)
Xie XG, Jiang HJ, Sun K, Zhao YY, Li XG, Han T, Chen Y, Dai CC.   +7 more
europepmc   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Bone Tissue Engineering: Recent Advances and Translation to Clinical Application. [PDF]

J Funct Biomater
Guastaldi FPS, Mahadik B.
europepmc   +1 more source

[Editorial: Biological availability of drugs].

Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1974
P, Flatberg, P K, Lunde
openaire   +1 more source