Results 91 to 100 of about 12,079,690 (308)
Annual Report - Marine Biological Laboratory, 1989
Annual report of the Marine Biological Laboratory in Woods Hole. 1989.
Marine Biological Laboratory (Woods Hole MA)
core
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Annual Report - Marine Biological Laboratory, 1893
Annual report of the Marine Biological Laboratory in Woods Hole. 1893.
Marine Biological Laboratory (Woods Hole MA)
core
Tracing holotype trajectories: Mapping the movement of the most valuable herbarium specimens
Societal Impact Statement Global efforts to protect biodiversity depend on fair access to key plant specimens. This study examines the distribution of 119,361 holotypes—unique herbarium specimens used to formally describe new plant species.
Dominik Tomaszewski +2 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Annual Report - Marine Biological Laboratory, 1903-1906
https://hdl.handle.net/1912/21944Marine Biological Laboratory.
Marine Biological Laboratory (Woods Hole MA)
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Annual Report - Marine Biological Laboratory, 1890
Annual report of the Marine Biological Laboratory in Woods Hole. 1890.
Marine Biological Laboratory (Woods Hole MA)
core
Generation and Collection of Biological Nanoaerosols
The report describes new technologies in generation and collection of biological nanoaerosol (NA) developed in the laboratory of Nanostructures and Nanotechnologies, ITEB RAS. NA generator to be used for pulmonary delivery of antibiotics, anti-inflammatory and other drugs and vaccines employs a new atomization principle based on a gas-phase ...
Morozov, V.N. +3 more
openaire +2 more sources
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source

