Results 81 to 90 of about 12,079,690 (308)

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Annual Report - Marine Biological Laboratory, 1917

, 1918
Annual report of the Marine Biological Laboratory in Woods Hole. 1917.
Marine Biological Laboratory (Woods Hole MA)
core  

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Annual Report - Marine Biological Laboratory, 1934

, 1935
Annual report of the Marine Biological Laboratory in Woods Hole. 1934.
Marine Biological Laboratory (Woods Hole MA)
core  

Rare plant species of the Caucasian flora in the herbarium of the M.M. Gryshko National Botanical Garden of the NAS of Ukraine (KWHA): representativeness and chorology

Інтродукція Рослин
The Caucasus is one of the floristically richest regions of temperate Eurasia, characterized by high endemism and an exceptional diversity of rare and threatened vascular plant species.
Oleksandr Shynder, Tetyana Bahatska
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Annual Report - Marine Biological Laboratory, 1929

, 1930
Annual report of the Marine Biological Laboratory in Woods Hole. 1929.
Marine Biological Laboratory (Woods Hole MA)
core  

Bryophytes Collection of the University of Brasilia Herbarium, Brazil

Diversity
The UB Herbarium, located in the Department of Botany at the University of Brasilia (Brasilia, Brazil), was established in 1963. It is the third-largest herbarium in Brazil, housing approximately 277,000 samples.
Mel C. Camelo, Allan L. A. Faria, Daniela Cemin, Paulo E. A. S. Câmara, Micheline Carvalho-Silva   +4 more
doaj   +1 more source

Strengthening the global network for sharing of marine biological collections: recommendations for a new agreement for biodiversity beyond national jurisdiction. [PDF]

ICES J Mar Sci, 2021
Collins JE, Rabone M, Vanagt T, Amon DJ, Gobin J, Huys I.   +5 more
europepmc   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source