Results 61 to 70 of about 12,079,690 (308)
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Biological collections house millions of specimens with digital images increasingly available through open‐access platforms. However, most imaging protocols were developed for human interpretation without considering automated analysis requirements.
Alyson East +27 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Proceedings of the Biological Society of Washington.
Vol. 1 issued also in Smithsonian Institution, miscellaneous collections, v. 25; Vol. 2 issued also as Smithsonian Institution, miscellaneous publication, no. 545.Supplements accompany some vols.Mode of access: Internet.Vol.
Smithsonian Institution. +1 more
core
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Annual Report - Marine Biological Laboratory, 1895
Annual report of the Marine Biological Laboratory in Woods Hole. 1895.
Marine Biological Laboratory (Woods Hole MA)
core
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Annual Report - Marine Biological Laboratory, 1966
Annual report of the Marine Biological Laboratory in Woods Hole. 1966.
Marine Biological Laboratory (Woods Hole MA)
core
Notice_on_Potentially_Offensive_Historical_Language_and_Content_FINAL
Archives and Special Collections statement of potentially offensive or harmful historical language and/or ...
Archives and Special Collections
core +1 more source

