Results 111 to 120 of about 5,458,821 (345)

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Biological control possibility for house flies

open access: yesCalifornia Agriculture, 1964
One phase of integrated fly control studies on poultry ranches in northern California involves research on several natural enemies of the house fly, Musca domestica L, the little house fly, Fannia canicularis (L), and other nuisance flies The black ...
J Anderson, J Poorbaugh
doaj  

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Biological control of two avocado pests

open access: yesCalifornia Agriculture, 1985
When Amorbia cuneana and omnivorous looper show signs of building up, releases of an egg parasite can effectively augment natural control.
E Oatman, G Platner
doaj  

Multigenerational Rearing on Non-Prey Foods Does Not Affect Prey (Aphid) Recognition Behavior of Coleomegilla maculata (Coleoptera: Coccinellidae)

open access: yesInsects
The pink spotted lady beetle Coleomegilla maculata has been identified as a promising predator to mass rear and release into greenhouses and high tunnels to control aphids on small fruits and vegetables.
Eric W. Riddick   +2 more
doaj   +1 more source

Monitoring and controlling of process parameters in the biological phase of wastewater treatment

open access: bronze, 2020
Costel-Cătălin Prăjanu   +3 more
openalex   +2 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

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