Results 61 to 70 of about 1,829,061 (296)

Host defence peptide LEAP2 contributes to antimicrobial activity in a mustache toad (Leptobrachium liui)

open access: yesBMC Veterinary Research, 2023
Background The liver-expressed antimicrobial peptide 2 (LEAP2) is essential in host immunity against harmful pathogens and is only known to act as an extracellular modulator to regulate embryonic development in amphibians.
Jie Chen   +6 more
doaj   +1 more source

Snake eels (Ophichthidae) of the remote St. Peter and St. Paul’s Archipelago (Equatorial Atlantic) : Museum records after 37 years of shelf life [PDF]

open access: yes, 2019
Despite of its major zoogeographical interest, the biological diversity of central Atlantic oceanic islands are still poorly known because of its remoteness.
Luiz Jr., Omar J., McCosker, John E.
core  

Increasing turnover through time in tropical forests [PDF]

open access: yes, 1994
Tree turnover rates were assessed at 40 tropical forest sites. Averaged across inventoried forests, turnover, as measured by tree mortality and recruitment, has increased since the 1950's, with an apparent pantropical acceleration since 1980.
Gentry, A.H., Phillips, O.L.
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Philosophical Accounts of Biological Functions [PDF]

open access: yes, 2017
The book A critical overview of biological functions is a short monograph by J. Garson, which provides a survey of the views on biological functions in the analytic tradition of philosophy.
Montévil, Maël
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Assessing functional novelty of PSI structures via structure-function analysis of large and diverse superfamilies [PDF]

open access: yes, 2008
The structural genomics initiatives have had as one of their aims to improve our understanding of protein function by providing representative structures for many structurally uncharacterised protein families. As suggested by the recent assessment of the
Benoit H. Dessailly   +2 more
core   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Variation and evolution of polyadenylation profiles in sauropsid mitochondrial mRNAs as deduced from the high-throughput RNA sequencing

open access: yesBMC Genomics, 2017
Background Genes encoded in vertebrate mitochondrial DNAs are transcribed as a polycistronic transcript for both strands, which is later processed into individual mRNAs, rRNAs and tRNAs, followed by modifications, such as polyadenylation at the 3′ end of
Yao Sun   +3 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Home - About - Disclaimer - Privacy