Results 111 to 120 of about 2,108,914 (342)

Review for "An innovative strategy to recycle permeate in biologics continuous manufacturing process to improve material efficiency and sustainability"

, 2022

openalex   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Production of Flammulina velutipes on coffee husk and coffee spent-ground

Brazilian Archives of Biology and Technology, 2001
Solid state cultivation (SSC) was carried out to evaluate the feasibility of using coffee husk and spent-ground as substrates for the production of edible mushroom Flammulina under different conditions of moisture and spawn rate.
Fan Leifa, Ashok Pandey, Carlos R. Soccol   +2 more
doaj   +1 more source

High-efficient synthesis and biological activities of allosamidins

Journal of Enzyme Inhibition and Medicinal Chemistry, 2014
The pseudo-trisaccharide allosamidin 1 is a potent inhibitor of all family-18 chitinases, and it is confirmed to have insecticidal and antifungal activities. But the synthesis of allosamidins is very difficult, and it is a challengeable subject. Allosamidins were synthesized in solid-liquid phase, total solid-phase and total liquid-phase, respectively.
Gangliang, Huang, Daquan, Peng, Xinya, Mei, Xin, Chen, Feng, Xiao, Qilin, Tang   +5 more
openaire   +2 more sources

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

EFFICIENCY OF APPLICATION OF BIOLOGICALLY ACTIVE PRODUCTS ON SOYBEAN CROPS IN THE CONDITIONS OF THE NON-BLACK SOIL ZONE OF THE RUSSIAN FEDERATION [PDF]

, 2021
Marina Evgenievna Belyshkina
openalex   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Promoting Yield and Oyster Mushroom Cycle Production by Using Date Kernel and Wheat Straw Mixture as a Cultivation Substrate

BioResources
Mushroom production can contribute to food security through producing food of high nutritional value and medicinal interest. This study examined the effectiveness of using date kernel (K) in a mixture with wheat straw (WS) as substrate on yield and ...
Ghada Lamraoui, Choukri Tefiani, Asma Maouedj, Abdelmalek Chaalel, Nerdjes Spiga, Diego Cunha Zied, Salim Rouar, Kab-Yeul Jang, Fehmi Boufahja, Walid Elfalleh, Hamdi Bendif   +10 more
doaj  

Study of Biological Efficiency Biological Active Additive “Avena-Uz”

International Journal of Current Research and Review, 2021
Farmanova Nodira Takhirovna, Nurullayeva Dilobar Khamid Qizi, Sultanova Rano Khakimovna, Abdurahmonova Sabohat Abdugabarovna   +3 more
openaire   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source