Results 131 to 140 of about 10,327,060 (336)
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Kuwait Journal of SciencePleurotus species are grown because of their high yield potential, high nutritional and therapeutic value, and ease of growth. This research aimed to evaluate the yield and antioxidant activities of Pleurotus sajor-caju M2345 and Pleurotus ostreatus ...
Tirngo Begashaw, Asmamaw Tesfaw
doaj +1 more source
Biological efficiency of Agaricus brasiliensis cultivated in compost with nitrogen concentrations
, 2011 The production of compost is one of the most important steps for the cultivation of any species of mushroom. For the Agaricus species, this step is even more complex because it depends on the performance of different microorganisms that act on the ...
F. Siqueira +4 more
semanticscholar +1 more source
High-efficient synthesis and biological activities of allosamidins
Journal of Enzyme Inhibition and Medicinal Chemistry, 2014 The pseudo-trisaccharide allosamidin 1 is a potent inhibitor of all family-18 chitinases, and it is confirmed to have insecticidal and antifungal activities. But the synthesis of allosamidins is very difficult, and it is a challengeable subject. Allosamidins were synthesized in solid-liquid phase, total solid-phase and total liquid-phase, respectively.
Gangliang, Huang +5 more
openaire +2 more sources
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Зерновое хозяйство России, 2018 The results of three-year use of fungicides in laboratory and in the field have been considered. The substantiation of their biological and economic efficiency against harmful diseases in Tambov region has been given.
V. A. Lavrinova, I. M. Evseeva
doaj
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Production of Flammulina velutipes on coffee husk and coffee spent-ground
Brazilian Archives of Biology and Technology, 2001 Solid state cultivation (SSC) was carried out to evaluate the feasibility of using coffee husk and spent-ground as substrates for the production of edible mushroom Flammulina under different conditions of moisture and spawn rate.
Fan Leifa +2 more
doaj +1 more source
Study of Biological Efficiency Biological Active Additive “Avena-Uz”
International Journal of Current Research and Review, 2021 Farmanova Nodira Takhirovna +3 more
openaire +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source