Results 141 to 150 of about 1,034,919 (313)
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
FACTORS AFFECTING THE BIOLOGICAL PHOSPHORUS REMOVAL EFFICIENCY
, 1991 This paper reviews the most important factors having effect on the efficiency of enhanced biological phosphorus removal. The influent sewage characteristics relevant to the topic are discussed. The possibilities to avoid the impairing effects of nitrates
Csiti, A.
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Efficiency of Biological Utilization of Micronutrients by Forests Species in Hypoxerophytic Caatinga
, 2018 The study aimed to estimate the concentrations and efficiency of biological utilization of Cu, Fe, Zn, and Mn and the leaf biomass of ten species in a hypoxerophytic Caatinga fragment, aiming to contribute to a more adequate choice of species for ...
Alcienia Silva Albuquerque (5765063) +14 more
core +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
TRADABLE RISK PERMITS TO PREVENT FUTURE INTRODUCTIONS OF ALIEN INVASIVE SPECIES INTO THE GREAT LAKES
Alien invasive species contribute to biodiversity loss and cause billions of dollars of economic damage in the Great Lakes. We examine the design and efficiency of a tradeable permit system for biological pollution due to alien species that invade the ...
Horan, Richard D., Lupi, Frank
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The efficiency of education in generating literacy: a stochastic frontier approach [PDF]
The growing importance attached to education as a key factor to improve economic performance coupled with the persistent scarcity of resources for education makes it important that skills and literacy are produced efficiently.
Groot, W. +2 more
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Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Modifying Surber sampling technique increases capture of freshwater crabs in African upland streams
, 2012 We compared 2 methods for sampling the freshwater crab Potamonautes odhneri (Colosi) in Kenyan streams: standard Surber sampling, in which a sample is taken over a period of several minutes; and rapid Surber sampling, in which the process is reduced to ...
Michael Dobson; Freshwater Biological Association +2 more
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The Right-Sized Cow for Emerging and Commercial Beef Farmers in Semi-Arid South Africa: Connecting Biological and Economic Efficiency [PDF]
The study investigates the right size of cow in terms of both biological and economic efficiency under a typical production system in semi-arid South Africa.
Antwi, M.A., Venter, T.M., Oduniyi, O.S.
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source