Results 111 to 120 of about 1,034,919 (313)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Promoting Yield and Oyster Mushroom Cycle Production by Using Date Kernel and Wheat Straw Mixture as a Cultivation Substrate

BioResources
Mushroom production can contribute to food security through producing food of high nutritional value and medicinal interest. This study examined the effectiveness of using date kernel (K) in a mixture with wheat straw (WS) as substrate on yield and ...
Ghada Lamraoui, Choukri Tefiani, Asma Maouedj, Abdelmalek Chaalel, Nerdjes Spiga, Diego Cunha Zied, Salim Rouar, Kab-Yeul Jang, Fehmi Boufahja, Walid Elfalleh, Hamdi Bendif   +10 more
doaj  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Optimization, Path Dependence and the Law: Can Judges Promote Efficiency? [PDF]

The thesis that judges could (voluntarily or not) promote efficiency through their decisions has largely been discussed since Posner put it forward in the early 1970s.
Khalil, Elias L., Marciano, Alain
core  

An Efficient Apparatus for the Redistillation of Water for Biological Purposes

Experimental Biology and Medicine, 1953
The preparation of water of sufficient purity for critical biological work, and in sufficient quantity, is a perennial problem in biological research laboratories. It is generally agreed that the output of metallic stills such as those of block tin is likely to prove unsatisfactory.
openaire   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

A Theory of Efficiency Wage with Community-Based Income Sharing [PDF]

This paper uses efficiency wage theory and the existence of community based sharing to hypothesize that labor markets in developing countries have multiple equilibria--the same economy can be stuck at different levels of unemployment with different ...
Felkey, Amanda, Basu, Kaushik
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Tratamentos térmicos do calxisto para uso como camada de cobertura no cultivo de Agaricus brasiliensis Thermal treatments on lime schist casing layer for Agaricus brasiliensis cultivation

Ciência Rural, 2010
A escolha da camada de cobertura é uma das mais importantes etapas do cultivo de Agaricus brasiliensis. Apesar dessa importância, poucos estudos relatam o uso de diferentes tratamentos térmicos para o controle da microbiota em camadas de cobertura ...
Nelson Barros Colauto, Adriano Reis da Silveira, Augusto Ferreira da Eira, Giani Andrea Linde   +3 more
doaj  

Comparative Analysis of Main Agronomic Traits of Different Pleurotus giganteus Germplasm Resources

Life
Agronomic traits are key components in variety protection, cultivar development, and the formulation of DUS (distinct, uniform, and stable) test guidelines. P. giganteus is an increasingly popular and commercially promising edible macrofungi.
Miaomiao Yan, Dandan Zhai, Qiaozhen Li, Meiyan Zhang, Ning Jiang, Jianyu Liu, Chunyan Song, Xiaodong Shang, Hongyu Chen, Hailong Yu   +9 more
doaj   +1 more source