Results 111 to 120 of about 970,591 (266)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Optimizing Pleurotus ostreatus Mushroom Cultivation on Various Agro-Industrial By-Products—Development of a Process Analytical Technology Tool for Predicting Biological Efficiency

Fermentation
Pleurotus ostreatus is among the most widely cultivated mushroom species on a global scale, valued for its relative ease of cultivation, excellent organoleptic qualities, and notable nutraceutical properties. P.
Georgios Bekiaris, Christos S. Pappas, Athanasios Mastrogiannis, Lefteris Lachouvaris, Petros A. Tarantilis, Georgios I. Zervakis   +5 more
doaj   +1 more source

Induction of a higher-ordered architecture in glatiramer acetate improves its biological efficiency in an animal model of multiple sclerosis. [PDF]

Biomater Sci, 2020
Song Z, Khaw YM, Pacheco LA, Tseng KY, Tan Z, Cai K, Ponnusamy E, Cheng J, Inoue M.   +8 more
europepmc   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Exploring the potential of new Bacillus subtilis strain VKM B-3516D against common wheat diseases for sustainable farming system

Frontiers in Sustainable Food Systems
The present study evaluated the efficacy of a novel strain of Bacillus subtilis Krd-20 (VKM B-3516D) (Ehrenberg 1835) Cohn 1872 in controlling common wheat diseases.
Serguey V. Kopiltsov, Irina L. Astapchuk, Anastasia V. Elisyutikova, Lev V. Nazarenko, Nyasha J. Kavhiza, Olga D. Kucher, Aleksandra O. Utkina, Nazih Y. Rebouh   +7 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Evaluation of growth and production of Pleurotus sp. in sterilized substrates

Arquivos do Instituto Biológico
The gender Pleurotus is also known as oyster mushroom, shimeji or hiratake. Aiming to select the best substrates to cultivate two species of Pleurotus, this work measured vigor, mycelium growth (cm.day-1), fresh mass (g), productivity (%) and biological ...
Eduardo Bernardi, Elisandra Minotto, José Soares do Nascimento   +2 more
doaj  

Evaluation of the Biological Efficiency of Silver Nanoparticles Biosynthesized Using Croton tiglium L. Seeds Extract against Azoxymethane Induced Colon Cancer in Rats. [PDF]

Asian Pac J Cancer Prev, 2020
Aboulthana WM, Ibrahim NE, Osman NM, Seif MM, Hassan AK, Youssef AM, El-Feky AM, Madboli AA.   +7 more
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source