Results 51 to 60 of about 5,611,755 (345)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Chapter 2: Nanoscale Robotic Agents in Biological Fluids and Tissues

open access: yes, 2018
Nanorobots are untethered structures of sub-micron size that can be controlled in a non-trivial way. Such nanoscale robotic agents are envisioned to revolutionize medicine by enabling minimally invasive diagnostic and therapeutic procedures. To be useful,
Qiu, T.   +8 more
core   +1 more source

distribution of mercury in biological fluids

open access: yesمجلة كلية الطب, 2005
Background:
hala Ghazi Al- GEBOORI
doaj  

Wearable Biosensors: An Alternative and Practical Approach in Healthcare and Disease Monitoring

open access: yesMolecules, 2021
With the increasing prevalence of growing population, aging and chronic diseases continuously rising healthcare costs, the healthcare system is undergoing a vital transformation from the traditional hospital-centered system to an individual-centered ...
Atul Sharma   +3 more
doaj   +1 more source

Microdetermination of dihydroxyacetone in biological fluids [PDF]

open access: yesAnalytical Biochemistry, 1961
Abstract Dihydroxyacetone is reacted with an excess of 2,4-dinitrophenylhydrazine. The excess reagent is removed by the addition of pyruvic acid and followed by partition between benzene and sodium bicarbonate solution. The benzene layer containing the 2,4-dinitrophenylosazone of dihydroxyacetone is evaporated, and the color developed with the ...
Tsao, Makepeace U., Schwartz, E. L.
openaire   +3 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Paper-based microfluidic devices: Fabrication, detection, and significant applications in various fields

open access: yesReviews in Analytical Chemistry, 2022
Paper is the most abundant and inexpensive polymeric structure of cellulose available. Paper has micro-porous capillary-like networks which are responsible for flow of solvents instead of pumps or electronic power, making paper an ideally usable tool ...
Das Shibam, Gagandeep, Bhatia Rohit
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Numerical Computation of Hybrid Morphologies of Nanoparticles on the Dynamic of Nanofluid: The Case of Blood-Based Fluid

open access: yesAxioms, 2023
The movement of biological fluids in the human body is a premium field of interest to overcome growing biomedical challenges. Blood behavior shows different behavior in capillaries, veins, and arteries during circulation.
Meznah M. Alanazi   +6 more
doaj   +1 more source

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