Results 61 to 70 of about 5,611,755 (345)
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Sensors for the Detection of Biological Fluids
, 2020 Any criminal investigation begins with evidence collection and analysis. A lot of this evidence relies on the biological signatures left on it by the personnel who were present when the crime was committed.
Shubhankar Dube +9 more
core +1 more source
Assay of Properdin in Biological Fluids.
Experimental Biology and Medicine, 1957 Summary1. A sensitive, reproducible assay for properdin is described using spectro-photometric determinations of C'3 content. 2. RP and R3 reagent sera for the properdin assay may be readily prepared from guinea pig serum. 3. RP and R3 from both human and guinea pig sources may be used interchangeably in the reported properdin assay. 4.
openaire +2 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Microdevices for Locomotion in Complex Biological Fluids
, 2016 Locomotion is an essential feature for survival of many organisms, and it is also a technical requirement for untethered biomedical microdevices to operate inside the human body for targeted drug delivery and minimally invasive surgery.
Qiu, T., Qiu, Tian
core +1 more source
Evaluation of the Microbiome Identification of Forensically Relevant Biological Fluids: A Pilot Study. [PDF]
Diagnostics (Basel)In forensic sciences, body fluids, or biological traces, are a major source of information, and their identification can play a decisive role in criminal investigations.
Gouello A +6 more
europepmc +2 more sources
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Micropropulsion and microrheology in complex fluids via symmetry breaking
, 2012 Many biological fluids have polymeric microstructures and display non-Newtonian rheology. We take advantage of such nonlinear fluid behavior and combine it with geometrical symmetry-breaking to design a novel small-scale propeller able to move only in ...
Eric Lauga +7 more
core +1 more source
Open Chemistry, 2021 A human intoxication incident attributed to pesticide abuse was investigated using cutting-edge analytical methodologies. An LC-ESI-MS/MS method, based on a hybrid solid-phase extraction protocol (hybrid-SPE), was applied for the detection and ...
Kasiotis Konstantinos M. +5 more
doaj +1 more source