Results 81 to 90 of about 5,611,755 (345)

Supercritical fluids applications in nanomedicine

, 2015
Nanomedicine consists of the application of nanotechnologies in the medical field. In many nanomedical applications, supercritical fluids based processes represent the best potential choice, since they allow controlled fabrication of biological active ...
BALDINO, LUCIA, REVERCHON, Ernesto, Reverchon E., Baldino L., CAMPARDELLI, ROBERTA, Campardelli R.   +5 more
core   +1 more source

Deep-sequencing of microRNA associated with Alzheimer’s disease in biological fluids: From biomarker discovery to diagnostic practice

Frontiers in Genetics, 2013
Diagnostic tools for neurodegenerative diseases such as Alzheimer's disease (AD) currently involve subjective neuropsychological testing and specialised brain imaging techniques.
Lesley eCheng, Camelia eQuek, Xin eSun, Shayne Anthony Bellingham, Andrew Francis Hill   +4 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Métodos de extração e/ou concentração de compostos encontrados em fluidos biológicos para posterior determinação cromatográfica Methods of extraction and/or concentration of compounds found in biological fluids for subsequent chromatographic determination

Química Nova, 2001
When organic compounds present in biological fluids are analysed by chromatographic methods, it is generally necessary to carry out a prior sample preparation due the high complexity of this type of sample, especially when the compounds to be ...
Sonia C. N. Queiroz, Carol H. Collins, Isabel C. S. F. Jardim   +2 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Micro- and nanorobots in Newtonian and biological viscoelastic fluids

, 2017
Swimming microorganisms are a source of inspiration for small scale robots that are intended to operate in fluidic environments including complex biomedical fluids.
Qiu, T., Fischer, P., Debora Walker, Walker, D., Stefano Palagi, Palagi, S., Tian Qiu, Peer Fischer, Fischer, P. ; https://orcid.org/   +8 more
core   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Biological microsystem for measuring uric acid in biological fluids [PDF]

, 2004
This paper describes a biological microsystem (bio-system) for measuring uric acid concentration in serum, plasma or urine. Its operation is based on optical absorption in a well-defined part of the visible spectrum.
Minas, Graça, Ribeiro, J. C., Martins, Júlio S., Correia, J. H., Wolffenbuttel, R. F.   +4 more
core   +1 more source

Tribological performance of the biological components of synovial fluid in artificial joint implants

Science and Technology of Advanced Materials, 2015
The concentration of biological components of synovial fluid (such as albumin, globulin, hyaluronic acid, and lubricin) varies between healthy persons and osteoarthritis (OA) patients.
Subir Ghosh, Dipankar Choudhury, Taposh Roy, Ali Moradi, H H Masjuki, Belinda Pingguan-Murphy   +5 more
doaj   +1 more source

Bioanalytical and Mass Spectrometric Methods for Aldehyde Profiling in Biological Fluids

Toxics, 2019
Human exposure to aldehydes is implicated in multiple diseases including diabetes, cardiovascular diseases, neurodegenerative disorders (i.e., Alzheimer’s and Parkinson’s Diseases), and cancer. Because these compounds are strong electrophiles,
Romel P. Dator, Morwena J. Solivio, Peter W. Villalta, Silvia Balbo   +3 more
doaj   +1 more source