Results 21 to 30 of about 2,475,642 (267)
Fibroblast Growth Factor Receptors (FGFRs) and Noncanonical Partners in Cancer Signaling
Cells, 2021 Increasing evidence indicates that success of targeted therapies in the treatment of cancer is context-dependent and is influenced by a complex crosstalk between signaling pathways and between cell types in the tumor.
Harriet R. Ferguson +2 more
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Biological functions of entactin
Kidney International, 1993 Entactin is a sulfated multidomain glycoprotein component of basement membranes. The molecule consists of 1217 amino acids which are organized into two terminal globular domains linked by a rod-like structure largely composed of four EGF- and one thyroglobulin-like cysteine-rich homology repeats.
Chung, Albert E. +3 more
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The biological function of consciousness [PDF]
Frontiers in Psychology, 2014 This research is an investigation of whether consciousness-one's ongoing experience-influences one's behavior and, if so, how. Analysis of the components, structure, properties, and temporal sequences of consciousness has established that, (1) contrary to one's intuitive understanding, consciousness does not have an active, executive role in ...
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Ipomoeassin-F disrupts multiple aspects of secretory protein biogenesis
Scientific Reports, 2021 The Sec61 complex translocates nascent polypeptides into and across the membrane of the endoplasmic reticulum (ER), providing access to the secretory pathway. In this study, we show that Ipomoeassin-F (Ipom-F), a selective inhibitor of protein entry into
Peristera Roboti +4 more
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Nature Communications, 2023 Adipose tissue invariant natural killer T (iNKT) cells are a crucial cell type for adipose tissue homeostasis in obese animals. However, heterogeneity of adipose iNKT cells and their function in adipocyte turnover are not thoroughly understood.
Sang Mun Han +15 more
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Intertwined and Finely Balanced: Endoplasmic Reticulum Morphology, Dynamics, Function, and Diseases
Cells, 2021 The endoplasmic reticulum (ER) is an organelle that is responsible for many essential subcellular processes. Interconnected narrow tubules at the periphery and thicker sheet-like regions in the perinuclear region are linked to the nuclear envelope. It is
Hannah T. Perkins, Viki Allan
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Transversal: International Journal for the Historiography of Science, 2022 Eliminativism is a peripheral (if not dead) position in the current biological function debate, and it is roughly presented as the thesis that function terms are eliminable in biological discourse. While eliminativism is often assumed inadequate, a detailed examination of eliminativism is lacking in current literature.
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Frontiers in Nutrition, 2022 Metabolic syndrome (MS) is a metabolic disorder that arises from the increasing prevalence of obesity. The pathophysiology seems to be largely attributable to the imbalance of lipid and glucose metabolism, redox signaling pathways, and gut microbiota ...
Xixin Zhou +8 more
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Biological functions of biotinylated histones [PDF]
The Journal of Nutritional Biochemistry, 2005 Histones H1, H2A, H2B, H3 and H4 are DNA-binding proteins that mediate the folding of DNA into chromatin. Various posttranslational modifications of histones regulate processes such as transcription, replication and repair of DNA. Recently, a novel posttranslational modification has been identified: covalent binding of the vitamin biotin to lysine ...
Nagarama, Kothapalli +6 more
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Nature Communications, 2022 High-crystallinity poly(ethylene terephthalate) is a major recycling challenge. Here, the authors show an engineered whole-cell biocatalyst showing adhesive hydrophobin and PETase on the surface of cells, for biodegradation of PET.
Zhuozhi Chen +14 more
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