Results 141 to 150 of about 4,841,906 (368)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Microbiome–volatile metabolome analysis reveals aroma regulation driven by microbial niche competition in Jinggang honey pomelo wine

Frontiers in Microbiology
IntroductionMicrobial succession in fruit wine has been reported, but the ecological mechanisms linking niche competition to aroma formation remain poorly understood.
Yang Wu, Yang Wu, Yang Wu, Weiwei Li, Weiwei Li, Weiwei Li, Jianan Shi, Jianan Shi, Jianan Shi, Zhihao Zhang, Cheng Jing, Cheng Jing, Cheng Jing, Jianqi Sheng, Jianqi Sheng, Jianqi Sheng, Zexia Li, Zexia Li, Zexia Li, Xiaowen Shi, Dingkun Liu, Dingkun Liu, Dingkun Liu, Li He, Li He, Li He, Huimin Sun, Huimin Sun, Huimin Sun   +28 more
doaj   +1 more source

Aliens on the Road: Surveying Wildlife Roadkill to Assess the Risk of Biological Invasion. [PDF]

Biology (Basel), 2023
Viviano A, D'Amico M, Mori E.
europepmc   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

A Modeling Framework to Frame a Biological Invasion: Impatiens glandulifera in North America. [PDF]

Plants (Basel), 2023
Kanmaz O, Şenel T, Dalfes HN.
europepmc   +1 more source

THE ECONOMICS OF CONTROLLING A BIOLOGICAL INVASION [PDF]

The paper develops a simple economic model of a biological invasion. The natural growth of the invasion is non-convex and the immediate cost of controlling the invasion depends on the level of current control as well as the current size of the invasion ...
Olson, Lars J., Roy, Santanu
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Uncertainty quantification for probabilistic machine learning in earth observation using conformal prediction

Scientific Reports
Machine learning is increasingly applied to Earth Observation (EO) data to obtain datasets that contribute towards international accords. However, these datasets contain inherent uncertainty that needs to be quantified reliably to avoid negative ...
Geethen Singh, Glenn Moncrieff, Zander Venter, Kerry Cawse-Nicholson, Jasper Slingsby, Tamara B. Robinson   +5 more
doaj   +1 more source

Alternative stable ecological states observed after a biological invasion. [PDF]

Sci Rep, 2022
Garcia AG, Mesquita Filho W, Flechtmann CAH, Lockwood JL, Bonachela JA.   +4 more
europepmc   +1 more source

A mathematical insight in the epithelial-mesenchymal-like transition in cancer cells and its effect in the invasion of the extracellular matrix

, 2015
Current biological knowledge supports the existence of a secondary group of cancer cells within the body of the tumour that exhibits stem cell-like properties.
Hellmann, Nadja, Kolbe, Niklas, Sfakianakis, Nikolaos   +2 more
core