Results 131 to 140 of about 768,999 (294)

Experimental Validation of the Predicted Binding Site of Escherichia coli K1 Outer Membrane Protein A to Human Brain Microvascular Endothelial Cells: Identification of Critical Mutations That Prevent E. coli Meningitis [PDF]

, 2010
Escherichia coli K1, the most common cause of meningitis in neonates, has been shown to interact with GlcNAc1–4GlcNAc epitopes of Ecgp96 on human brain microvascular endothelial cells (HBMECs) via OmpA (outer membrane protein A).
Abrol, Ravinder, Goddard, William A., III, Mittal, Rahul, Pascal, Tod A., Prasadarao, Nemani V., Wang, Ying   +5 more
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Bioinvasion risk analysis based on automatic identification system and marine ecoregion data

High-Confidence Computing
The global maritime trade plays a key role in propagating alien aquatic invasive species, which incurs side effects in terms of environment, human health and economy.
Hongwei Shi, Chenyu Wang, Hang Zhao, Shengling Wang, Yixian Chen   +4 more
doaj   +1 more source

Changes in selection pressure can facilitate hybridization during biological invasion in a Cuban lizard. [PDF]

Proc Natl Acad Sci U S A, 2021
Bock DG, Baeckens S, Pita-Aquino JN, Chejanovski ZA, Michaelides SN, Muralidhar P, Lapiedra O, Park S, Menke DB, Geneva AJ, Losos JB, Kolbe JJ.   +11 more
europepmc   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Uncertainty quantification for probabilistic machine learning in earth observation using conformal prediction

Scientific Reports
Machine learning is increasingly applied to Earth Observation (EO) data to obtain datasets that contribute towards international accords. However, these datasets contain inherent uncertainty that needs to be quantified reliably to avoid negative ...
Geethen Singh, Glenn Moncrieff, Zander Venter, Kerry Cawse-Nicholson, Jasper Slingsby, Tamara B. Robinson   +5 more
doaj   +1 more source

The Invasive Bank Vole (Myodes glareolus): A Model System for Studying Parasites and Ecoimmunology during a Biological Invasion. [PDF]

Animals (Basel), 2021
McManus A, Holland CV, Henttonen H, Stuart P.   +3 more
europepmc   +1 more source

THE ECONOMICS OF CONTROLLING A BIOLOGICAL INVASION [PDF]

The paper develops a simple economic model of a biological invasion. The natural growth of the invasion is non-convex and the immediate cost of controlling the invasion depends on the level of current control as well as the current size of the invasion ...
Olson, Lars J., Roy, Santanu
core   +1 more source

Homologous self-organising scale-invariant properties characterise long range species spread and cancer invasion [PDF]

, 2007
The invariance of some system properties over a range of temporal and/or spatial scales is an attribute of many processes in nature1, often characterised by power law functions and fractal geometry2.
Bo Hu, Diana D. E. Marco, Marcelo M. A. Montemurro, Sergio S. A. Cannas, Shiyuan Cheng   +4 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source