Results 111 to 120 of about 768,999 (294)

On Prevention and Control of an Uncertain Biological Invasion [PDF]

This paper examines how optimal prevention and control policies depend on the economic and biological characteristics of a randomly introduced biological invasion where the objective is to minimize the expected social costs from prevention, control, and ...
Olson, Lars J., Roy, Santanu
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

A biological invasion reduces rates of cannibalism by Japanese toad tadpoles. [PDF]

Sci Rep, 2023
Crossland MR, Shine R, Haramura T.
europepmc   +1 more source

Controlling the Biological Invasion of a Commercial Fishery by a Space Competitor: A Bioeconomic Model with Reference to the Bay of St-Brieuc Scallop Fishery [PDF]

This paper presents a bioeconomic model of a commercial fishery facing biological invasion by an alien species acting as a space competitor for the native species.
Boncoeur, Jean, Fresard, Marjolaine
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Climate change scenarios predict reduction in suitable habitats and range shifts for Ophiocordyceps sinensis (Berk.) in Hindu Kush Himalaya

Journal of Asia-Pacific Biodiversity
The Hindu Kush Himalayan region has seen a faster pace of anthropogenic climate warming than the global average during the last 50 years. Since the 1980s this region has been experiencing intense climatic events, notably elevation-dependent warming ...
Nadeem Salam, Harvinder Kaur Sidhu, Shaheeda Shaban, Zafar A. Reshi, Manzoor A. Shah   +4 more
doaj   +1 more source

Aliens on the Road: Surveying Wildlife Roadkill to Assess the Risk of Biological Invasion. [PDF]

Biology (Basel), 2023
Viviano A, D'Amico M, Mori E.
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

A Modeling Framework to Frame a Biological Invasion: Impatiens glandulifera in North America. [PDF]

Plants (Basel), 2023
Kanmaz O, Şenel T, Dalfes HN.
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source