Results 101 to 110 of about 405,367 (255)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

A single introduction of wild rabbits triggered the biological invasion of Australia. [PDF]

Proc Natl Acad Sci U S A, 2022
Alves JM, Carneiro M, Day JP, Welch JJ, Duckworth JA, Cox TE, Letnic M, Strive T, Ferrand N, Jiggins FM.   +9 more
europepmc   +1 more source

Biological invasions [PDF]

Current Biology, 2008
openaire   +2 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Evidence for continent-wide convergent evolution and stasis throughout 150 y of a biological invasion. [PDF]

Proc Natl Acad Sci U S A, 2022
Wu Y, Colautti RI.
europepmc   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Climate change scenarios predict reduction in suitable habitats and range shifts for Ophiocordyceps sinensis (Berk.) in Hindu Kush Himalaya

Journal of Asia-Pacific Biodiversity
The Hindu Kush Himalayan region has seen a faster pace of anthropogenic climate warming than the global average during the last 50 years. Since the 1980s this region has been experiencing intense climatic events, notably elevation-dependent warming ...
Nadeem Salam, Harvinder Kaur Sidhu, Shaheeda Shaban, Zafar A. Reshi, Manzoor A. Shah   +4 more
doaj   +1 more source

Genomics reveals the history of a complex plant invasion and improves the management of a biological invasion from the South African-Australian biotic exchange. [PDF]

Ecol Evol, 2022
Byrne D, Scheben A, Scott JK, Webber BL, Batchelor KL, Severn-Ellis AA, Gooden B, Bell KL.   +7 more
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Changes in selection pressure can facilitate hybridization during biological invasion in a Cuban lizard. [PDF]

Proc Natl Acad Sci U S A, 2021
Bock DG, Baeckens S, Pita-Aquino JN, Chejanovski ZA, Michaelides SN, Muralidhar P, Lapiedra O, Park S, Menke DB, Geneva AJ, Losos JB, Kolbe JJ.   +11 more
europepmc   +1 more source