Results 71 to 80 of about 768,999 (294)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Range expansion of an invasive species through a heterogeneous landscape - the case of American mink in Scotland [PDF]

, 2015
ACKNOWLEDGEMENTS We would like to thank Scottish Natural Heritage, particularly Iain Macleod and Rob Raynor, for data and funding.We are grateful to the Game and Wildlife Conservation Trust, especially Jonathan Reynolds, Vincent Wildlife Trust and ...
Aars, Aben, Allouche, Banks, Bocedi, Bonesi, Bryce, Craik, Cuthbert, Dunstone, Eskildsen, Fasola, Fraser, Freeman, Genovesi, Gerell, Getz, Gilbert, Gormley, Green, Green, Harrington, Hastings, Iordan, Jefferies, Jeschke, Kolbe, Lubina, Macdonald, Melero, Miller, Morgia, Nordström, Oliver, Peris, Rodrigues, Royle, Royle, Ruiz-Olmo, Sakai, Shigesada, Skellam, Strachan, Urban, Usher, White, With, Zalewski   +47 more
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Comparative Study of Hirudins and Encoding Genes in Hirudo nipponia and Hirudo tianjinensis

Biology
This study systematically compared the genetic characteristics and functional activities of hirudins and their encoding genes between Hirudo nipponia (Hnip1–3) and Hirudo tianjinensis (Htia1–3) through bioinformatics analysis, recombinant protein ...
Jingjing Yin, Zichao Liu, Yunfei Yu, Anping Wang, Zuhao Huang, Lizhou Tang, Fang Zhao, Gonghua Lin   +7 more
doaj   +1 more source

Skistodiaptomus pallidus (Copepoda: Diaptomidae) establishment in New Zealand natural lakes, and its effects on zooplankton community composition [PDF]

, 2014
The North American calanoid copepod Skistodiaptomus pallidus is an emerging invader globally, with non-indigenous populations recorded from constructed waters in New Zealand, Germany and Mexico since 2000. We examined the effects of S.
Duggan, Ian C., Neale, MW, Robinson, Karen V., Verburg, Piet, Watson, Nathan Thomas Noble   +4 more
core   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Deciphering mycobiota and its functional dynamics in root hairs of Rhododendron campanulatum D. Don through Next-gen sequencing

Scientific Reports
The Himalayas provide unique opportunities for the extension of shrubs beyond the upper limit of the tree. However, little is known about the limitation of the biotic factors belowground of shrub growth at these cruising altitudes.
Nafeesa Farooq Khan, Sheikh Sajad Ahmed, Mukhtar Iderawumi Abdulraheem, Zafar Ahmad Reshi, Abdul Wahab, Gholamreza Abdi   +5 more
doaj   +1 more source

Computational Methods and Results for Structured Multiscale Models of Tumor Invasion

, 2005
We present multiscale models of cancer tumor invasion with components at the molecular, cellular, and tissue levels. We provide biological justifications for the model components, present computational results from the model, and discuss the scientific ...
Anderson, Alexander R. A., Ayati, Bruce P., Webb, Glenn F.   +2 more
core  

The ‘grand scheme of things’: biological invasions, their detection, impacts and management [PDF]

, 2014
Editorial of Management of Biological Invasions: International Journal of Applied Research on Biological Invasions, Volume 5, Issues ...
Campbell, Marnie L., MacNeil, Calum
core   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source