Results 61 to 70 of about 405,367 (255)

A comparative study on population status, nesting strategies, and conservation of two bee-eater species in China

Global Ecology and Conservation
Among China’s bee-eaters (Meropidae), the blue-throated bee-eater (Merops viridis) and the blue-tailed bee-eater (M. philippinus) are both widely distributed and listed as second-class nationally protected species.
Dianhua Ke, Shiyan Xie, Haiying Fan, Weibin Guo, Yanhui Deng, Guanghong Chen, Haokang Luo, Zuhao Huang   +7 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Deciphering mycobiota and its functional dynamics in root hairs of Rhododendron campanulatum D. Don through Next-gen sequencing

Scientific Reports
The Himalayas provide unique opportunities for the extension of shrubs beyond the upper limit of the tree. However, little is known about the limitation of the biotic factors belowground of shrub growth at these cruising altitudes.
Nafeesa Farooq Khan, Sheikh Sajad Ahmed, Mukhtar Iderawumi Abdulraheem, Zafar Ahmad Reshi, Abdul Wahab, Gholamreza Abdi   +5 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Co-application of biochar and melatonin enhances rice resilience to combined lead and microplastics stress via modulating antioxidant defense, hormonal regulation, gene expression, and soil quality

BMC Plant Biology
Background Microplastics (MPs) pollution is becoming a serious challenge and poses ecological risks. MPs are known to interact with heavy metals, such as lead (Pb), adversely impacting plant growth.
Jie Du, Wenjie Yang, Jiayong Liu, Zhixuan Du   +3 more
doaj   +1 more source

Comparative Study of Hirudins and Encoding Genes in Hirudo nipponia and Hirudo tianjinensis

Biology
This study systematically compared the genetic characteristics and functional activities of hirudins and their encoding genes between Hirudo nipponia (Hnip1–3) and Hirudo tianjinensis (Htia1–3) through bioinformatics analysis, recombinant protein ...
Jingjing Yin, Zichao Liu, Yunfei Yu, Anping Wang, Zuhao Huang, Lizhou Tang, Fang Zhao, Gonghua Lin   +7 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Characteristics of Floral Volatiles and Their Effects on Attracting Pollinating Insects in Three Bidens Species with Sympatric Distribution

Biology
The transition from outcrossing to self-pollination is an evolutionary process in angiosperms. However, the changes in floral volatile composition during this process and their impacts on the behavior of pollinators are poorly understood. Therefore, this
Jun-Wei Ye, Jing-Lin Jia, Yong-Hong Xiao, Jia-Hui Zhou, Jian-Jun Zeng   +4 more
doaj   +1 more source