Results 1 to 10 of about 1,368,371 (219)

Comparative effectiveness of H7N9 vaccines in healthy individuals

Human Vaccines & Immunotherapeutics, 2019
Background: Avian H7N9 influenza viruses possess a potential pandemic threat to public health worldwide, and have caused severe infection and high mortality in humans. A series of clinical trials of H7N9 vaccines have been completed.
Dan Zheng, Feixia Gao, Cheng Zhao, Yahong Ding, Yemin Cao, Tianhan Yang, Xuesong Xu, Ze Chen   +7 more
doaj   +1 more source

The Screening and Mechanism of Influenza-Virus Sensitive MDCK Cell Lines for Influenza Vaccine Production

Diseases
Influenza is a potentially fatal acute respiratory viral disease caused by the influenza virus. Influenza viruses vary in antigenicity and spread rapidly, resulting in seasonal epidemics.
Zhaona Yang, Shouzhi Yu, Ying Xu, Yuxiu Zhao, Lili Li, Jingjie Sun, Xin Wang, Yancen Guo, Yuntao Zhang   +8 more
doaj   +1 more source

Precise detection of differential RNA editing sites across varied biological conditions using the CADRES pipeline

Scientific Reports
RNA editing is an important post-transcriptional modification for gene regulation and protein diversity. Detecting these modifications, especially Differential Variants on RNA (DVRs), presents significant challenges due to interference from sequencing ...
Jun Sun, Chi Zhang, Xiuling Li
doaj   +1 more source

A single-dose mRNA vaccine induces potent and long-lasting humoral and cellular immunity against the varicella-zoster virus in a murine model

Frontiers in Immunology
IntroductionHerpes zoster is an infectious disease caused by the varicella-zoster virus (VZV). In adults, the reactivation of VZV can lead to severe neuralgia and skin rashes.
Wenyu Cheng, Ning Ren, Li Xie, Wenjin Zhou, Rui Quan, Heng Wei   +5 more
doaj   +1 more source

Follicle-Stimulating Hormone Biological Products: Does Potency Predict Clinical Efficacy? [PDF]

Int J Mol Sci, 2023
Lispi M, Humaidan P, Bousfield GR, D'Hooghe T, Ulloa-Aguirre A.   +4 more
europepmc   +1 more source

Expression and identification of a novel high-activity recombinant humanized type I collagen SynthCol1 in Pichia pastoris GS115

Applied Microbiology and Biotechnology
The limitations associated with animal-derived collagen, such as the risk of zoonotic pathogen transmission and batch variability, have expedited the development of recombinant alternatives.
Zhiwu Zhang, Jinyu Li, Zhengfeng Chen, Haiming Du, Wei Xia, Yana Wang, Huimin Yu   +6 more
doaj   +1 more source

Initial prescriptions and medication switches of biological products: an analysis of prescription pathways and determinants in the Swiss healthcare setting. [PDF]

BMJ Open, 2023
Wirth K, Boes S, Näpflin M, Huber C, Blozik E.   +4 more
europepmc   +1 more source

Raport privind controlul calitaţii microbiologice a produselor farmaceutice veterinare în anul 2014 / Report regarding the microbiological quality control of the veterinary pharmaceutical products during 2014 [PDF]

Medicamentul Veterinar, 2015
The microbiological contamination of pharmaceutical products could have major consequences on the physical – chemical characteristics, safety and efficiency of the medicinal products, on the out of specification products recall-associated costs and, very
Simona Sturzu , Daniela Tîrsînoagă, Ioana Tihulcă, Mariana Dumitrache, Alina Drăghici, Cristina Popica, Valentina Năstase   +6 more
doaj  

Next-Generation Sequencing: A Promising Tool for Vaccines and Other Biological Products. [PDF]

Vaccines (Basel), 2023
Nellimarla S, Kesanakurti P.
europepmc   +1 more source

Bayesian Methods in Human Drug and Biological Products Development in CDER and CBER. [PDF]

Ther Innov Regul Sci, 2023
Ionan AC, Clark J, Travis J, Amatya A, Scott J, Smith JP, Chattopadhyay S, Salerno MJ, Rothmann M.   +8 more
europepmc   +1 more source