Results 41 to 50 of about 6,406,516 (312)
Emerging Microbes and Infections, 2023 Influenza virus is a prominent cause of respiratory illness in humans. Current influenza vaccines offer strain-specific immunity, while provide limited protection against drifted strains.
Feifei Xiong +7 more
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Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Antiviral effect of chelerythrine chloride against tick-borne encephalitis virus
Virology JournalTick-borne encephalitis virus (TBEV) is a neurotropic Orthoflavivirus that causes severe encephalitis and long-term neurological sequelae. Due to the limited protection from existing vaccines and the absence of effective antiviral drugs, the prevention ...
Jiangdan Li +11 more
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Research Advances on the Stability of mRNA Vaccines
Viruses, 2023 Compared to other vaccines, the inherent properties of messenger RNA (mRNA) vaccines and their interaction with lipid nanoparticles make them considerably unstable throughout their life cycles, impacting their effectiveness and global accessibility.
Feiran Cheng +7 more
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Chemical and Biological Production of Cyclotides [PDF]
, 2015 Cyclotides are fascinating naturally occurring micro-proteins (≈30 residues long) present in several plant families, and display various biological properties such as protease inhibitory, anti-microbial, insecticidal, cytotoxic, anti-HIV and hormone-like activities.
Yilong, Li, Tao, Bi, Julio A, Camarero
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Trends in Biological Ammonia Production
BioTech, 2023 Food production heavily depends on ammonia-containing fertilizers to improve crop yield and profitability. However, ammonia production is challenged by huge energy demand, the release of ~2% of global CO2, and political instability. To mitigate this challenge, many research efforts have developed bioprocessing technologies to make biological ammonia ...
Adewale Adeniyi +4 more
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
VirusesAs SARS-CoV-2 continues to evolve and COVID-19 cases rapidly increase among children and adults, there is an urgent need for a safe and effective vaccine that can elicit systemic and mucosal humoral immunity to limit the emergence of new variants.
Zhi-Hui Yang +15 more
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Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Scientific ReportsTo evaluate the immunogenicity and safety profiles of lyophilized hepatitis A live attenuated vaccine (L-A-1 attenuated strain) after stabilizer formula optimization using non-human primates and various rodent models.
Yibo Wang +8 more
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