Results 61 to 70 of about 6,406,516 (312)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Advancements in extracellular vesicles biomanufacturing: a comprehensive overview of large-scale production and clinical research

open access: yesFrontiers in Bioengineering and Biotechnology
Extracellular vesicles (EVs) are nano-sized, membranous structures secreted by cells into the extracellular space, have attracted considerable attention in the field of biosciences for their role in intercellular communication in various physiological ...
Ziqian Li   +11 more
doaj   +1 more source

Comparative effectiveness of H7N9 vaccines in healthy individuals

open access: yesHuman Vaccines & Immunotherapeutics, 2019
Background: Avian H7N9 influenza viruses possess a potential pandemic threat to public health worldwide, and have caused severe infection and high mortality in humans. A series of clinical trials of H7N9 vaccines have been completed.
Dan Zheng   +7 more
doaj   +1 more source

Annual Report - Marine Biological Laboratory, 1895

open access: yes, 1896
Annual report of the Marine Biological Laboratory in Woods Hole. 1895.
Marine Biological Laboratory (Woods Hole MA)
core  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Evaluation of Stability, Inactivation, and Disinfection Effectiveness of Mpox Virus

open access: yesViruses
Background: Mpox virus (MPXV) infections have increased in many countries since May 2022, increasing demand for diagnostic tests and research on the virus.
Yuwei Li   +12 more
doaj   +1 more source

Annual Report - Marine Biological Laboratory, 1966

open access: yes, 1967
Annual report of the Marine Biological Laboratory in Woods Hole. 1966.
Marine Biological Laboratory (Woods Hole MA)
core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Annual Report - Marine Biological Laboratory, 1909

open access: yes, 1910
Annual report of the Marine Biological Laboratory in Woods Hole. 1909.
Marine Biological Laboratory (Woods Hole MA)
core  

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