Results 111 to 120 of about 10,008,274 (374)

Resistance-gene-directed discovery of a natural-product herbicide with a new mode of action. [PDF]

open access: yes, 2018
Bioactive natural products have evolved to inhibit specific cellular targets and have served as lead molecules for health and agricultural applications for the past century1-3.
Bat-Erdene, Undramaa   +9 more
core  

Antioxidants of natural plant origins: from sources to food industry applications [PDF]

open access: yes, 2019
ReviewIn recent years, great interest has been focused on using natural antioxidants in food products, due to studies indicating possible adverse effects that may be related to the consumption of synthetic antioxidants. A variety of plant materials are
Alves, Vitor D.   +2 more
core   +1 more source

Precise detection of differential RNA editing sites across varied biological conditions using the CADRES pipeline

open access: yesScientific Reports
RNA editing is an important post-transcriptional modification for gene regulation and protein diversity. Detecting these modifications, especially Differential Variants on RNA (DVRs), presents significant challenges due to interference from sequencing ...
Jun Sun, Chi Zhang, Xiuling Li
doaj   +1 more source

Purification tags markedly affect self‐aggregation of CPEB3

open access: yesFEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito   +6 more
wiley   +1 more source

Research of Rational Concentration of Oilseed Crops Meals in the Sandy Dough Semi-finished Product [PDF]

open access: yes, 2019
The work studies the rational concentration of meals of soya, sunflower and milk thistle in a sandy dough semi-product for improving healthy properties of ready products (biological value, stomach peristalsis, metabolism, saturation with vitamins and ...
Dzyundzya, O. (Oksana)   +9 more
core   +3 more sources

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

A mass spectrometry-guided genome mining approach for natural product peptidogenomics. [PDF]

open access: yes, 2011
Peptide natural products show broad biological properties and are commonly produced by orthogonal ribosomal and nonribosomal pathways in prokaryotes and eukaryotes.
Cimermancic, Peter   +8 more
core  

The Screening and Mechanism of Influenza-Virus Sensitive MDCK Cell Lines for Influenza Vaccine Production

open access: yesDiseases
Influenza is a potentially fatal acute respiratory viral disease caused by the influenza virus. Influenza viruses vary in antigenicity and spread rapidly, resulting in seasonal epidemics.
Zhaona Yang   +8 more
doaj   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

open access: yesFEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao   +7 more
wiley   +1 more source

The phase transition in random catalytic sets

open access: yes, 2005
The notion of (auto) catalytic networks has become a cornerstone in understanding the possibility of a sudden dramatic increase of diversity in biological evolution as well as in the evolution of social and economical systems.
J. A. Schumpeter   +7 more
core   +1 more source

Home - About - Disclaimer - Privacy