Results 111 to 120 of about 2,696,596 (307)
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia +5 more
wiley +1 more source
Putting Process and Product Conceptions of Natural Selection and Genetic Drift to the Test [PDF]
This paper argues for two claims. First, despite a persistent appearance to the contrary in the philosophy of biology literature, the question of whether natural selection and genetic drift should be defined as processes or as the products (or outcomes)
Pence, Charles H.
core
The Effect of the War upon Our Supply of Certain Economic Biological Products [PDF]
Heber W. Youngken
openalex +1 more source
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source
REQUIREMENTS ON CLINICAL TRIALS FOR VETERINARY PHARMACEUTICAL PRODUCTS FOR FISH [PDF]
Veterinary pharmaceutical products intended for use in fish should comply with all usual requirements regarding approval for marketing, according to the Order of the President of the National Sanitary Veterinary Agency and for Food Safety No.187/2007 ...
Simona Sturzu +5 more
doaj
Bayesian Methods in Human Drug and Biological Products Development in CDER and CBER. [PDF]
Ionan AC +8 more
europepmc +1 more source
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur +5 more
wiley +1 more source
A Review of the Establishment of the Seed Lot System in the Production of Biological Products and Its Importance. [PDF]
Soleimani S.
europepmc +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Lack of Significant Oncogenicity of Biological Products in Hamsters [PDF]
Claire B. Cox +5 more
openalex +2 more sources

