Results 131 to 140 of about 1,399,233 (310)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Removal of micropollutants from grey water : combining biological and physical/chemical processes

open access: yes, 2010
Grey water consists of the discharges from kitchen sinks, showers, baths, washing machines and hand basins. The amount of grey water produced per person in The Netherlands is about 90 Ld-1, accounting for up to 75 % of the wastewater volume produced by ...
Hernandez Leal, L.
core  

Biological Products [PDF]

open access: yesJournal of the American Medical Association, 1940
  +4 more sources

Uptake and Competition Among Biosimilar Biological Products in the US Medicare Fee-for-Service Population. [PDF]

open access: yesJ Gen Intern Med, 2022
Kozlowski S   +6 more
europepmc   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Synthesis and Biological Evaluation of Natural Products Derivatives

open access: yes, 2010
Natural products continue to be interesting building blocks for the preparation of different types of derivatives that could result useful for their pharmacological activity or for their potential as probes due to the compatibility of the natural ...
D. Passarella
core  

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Virome Characterization in Commercial Bovine Serum Batches-A Potentially Needed Testing Strategy for Biological Products. [PDF]

open access: yesViruses, 2021
Paim WP   +6 more
europepmc   +1 more source

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