Results 1 to 10 of about 318,338 (358)

Identification of the Optimal Pattern of the Injection and Dosage of DC Immunotherapy Using the Mathematical Models Based on Ordinary Differential Equations [PDF]

Iranian Journal of Immunology, 2022
Background: Mathematical modeling offers the possibility to select the optimal dose of a drug or vaccine. Considerable evidence show that many bacterial components can activate dendritic cells (DCs). Our previous report showed that multiple doses of DCs
Bahareh Zand, Samaneh Arab, Nasim Kheshtchin, Abazar Arabameri, Mahboubeh Ashourpour, Davoud Asemani, Ehsan Sharif-Paghaleh, Farshid Noorbakhsh, Jamshid Hadjati   +8 more
doaj   +1 more source

Probabilistic estimation of hydraulic fracture half-lengths: validating the Gaussian pressure-transient method with the traditional rate transient analysis-method (Wolfcamp case study)

Journal of Petroleum Exploration and Production Technology, 2023
Despite significant advancements in geomodelling technologies, accurately estimating hydraulic fracture half-length remains a challenging task. This paper introduces a detailed estimation approach using the Gaussian Pressure Transient (GPT) method, which
Dandi Alvayed, Mohammed Sofian Ali Khalid, Moaz Dafaalla, Ahmed Ali, Ahmed Farid Ibrahim, Ruud Weijermars   +5 more
doaj   +1 more source

CpG Islands of the Pig [PDF]

Genome Research, 1997
We describe an analysis of the CpG islands (CGIs) of the pig. We have used both database survey and a porcine genomic library that is enriched for CGIs. Approximately half of 41 pig genomic database sequences had CGIs with an average G + C content of 65.3%, an average CpG observed/expected frequency of 0.85, and an average size of 978 bp.
McQueen, H A, Clark, V H, Bird, A P, Yerle, M, Archibald, A L   +4 more
openaire   +3 more sources

Multi-neuronal refractory period adapts centrally generated behaviour to reward [PDF]

, 2012
Oscillating neuronal circuits, known as central pattern generators (CPGs), are responsible for generating rhythmic behaviours such as walking, breathing and chewing.
Anil K. Seth, Christopher A. Harris, Christopher L. Buckley, György Kemenes, Manabu Sakakibara, Michael O'Shea, Peter A. Passaro, Thomas Nowotny   +7 more
core   +7 more sources

CpG dinucleotides and the mutation rate of non-CpG DNA [PDF]

Genome Research, 2008
The neutral mutation rate is equal to the base substitution rate when the latter is not affected by natural selection. Differences between these rates may reveal that factors such as natural selection, linkage, or a mutator locus are affecting a given sequence.
Walser, J., Ponger, L., Furano, A. V.
openaire   +2 more sources

Preservation of methylated CpG dinucleotides in human CpG islands [PDF]

Biology Direct, 2016
CpG dinucleotides are extensively underrepresented in mammalian genomes. It is widely accepted that genome-wide CpG depletion is predominantly caused by an elevated CpG > TpG mutation rate due to frequent cytosine methylation in the CpG context. Meanwhile the CpG content in genomic regions called CpG islands (CGIs) is noticeably higher.
Panchin, Alexander Y., Makeev, Vsevolod J., Medvedeva, Yulia A.   +2 more
openaire   +2 more sources

Policy for developing clinical practice guidelines of Japanese Society for Dialysis Therapy

Renal Replacement Therapy, 2017
Background The Scientific Academy Committee of Japanese Society for Dialysis Therapy (JSDT) has developed 14 clinical practice guidelines (CPGs) and their revised editions independently or in cooperation with other organizations and translated many of ...
Kosaku Nitta, Ikuto Masakane, Tadashi Tomo, Kenji Tsuchida, Kiyoshi Ikeda, Tomonari Ogawa, Eiichiro Kanda, Yoshihiko Kanno, Yasuhiro Komatsu, Masatomo Taniguchi, Fumika Taki, Takeshi Hasegawa, Norio Hanafusa, Takayuki Hamano, Masafumi Fukagawa, Jun Minakuchi, Hiroyasu Yamamoto, Naoki Washida, Takashi Wada, Yuzo Watanabe, on behalf of the Scientific Academy Committee of Japanese Society for Dialysis Therapy (JSDT)   +20 more
doaj   +1 more source

Autonomous gait modulation in a cat hind leg simulation model based on the spinal nervous system

Nihon Kikai Gakkai ronbunshu, 2020
This study aims to design a nervous system model to drive the realistic muscle-driven legs for quadrupedal robot locomotion. In this paper, we evaluate the nervous system model.
Yasushi HABU, Junnya ISHIHARA, Kouta INOUE, Satoshi OGURA, Yasuhiro FUKUOKA   +4 more
doaj   +1 more source

CpG and Interleukin-15 Synergize to Enhance IFN-γ Production by Activated CD8+ T Cells [PDF]

, 2012
Interleukin-15 (IL-15) regulates the development and maintenance of memory CD8+ T cells. Paradoxically, we previously reported that IL-15 could enhance CD8+ T-cell responses to IL-12, a proinflammatory cytokine required for optimal priming of effector ...
Cobb, Dustin, Guo, Siqi, Smeltz, Ronald B.   +2 more
core   +5 more sources

Use of Urology-Based Clinical Practice Guidelines in International Settings

Société Internationale d’Urologie Journal, 2021
ObjectiveClinical practice guidelines (CPGs) serve as frameworks to unify diagnostic criteria and guide clinical decision-making. There is a paucity of literature surrounding the uptake of CPGs in urology practice settings with varied ...
German Patino, Medina Ndoye, Hannah Thomas, Andrew Cohen, Nnenaya Mmonu, Carissa Chu, Benjamin Breyer
doaj   +1 more source