Results 21 to 30 of about 155,959 (265)

Is inhaled immunotherapy more effective than environmental management when treating equine asthma?

open access: yesVeterinary Evidence, 2021
PICO question In horses with severe equine asthma syndrome, is inhaled immunotherapy compared to environmental reduction of allergen exposure more effective in disease modification?
Amy Leather, Sarah Smith
doaj   +1 more source

Synergy effects of Polyinosinic-polycytidylic acid, CpG oligodeoxynucleotide, and cationic peptides to adjuvant HPV E7 epitope vaccine through preventive and therapeutic immunization in a TC-1 grafted mouse model

open access: yesHuman Vaccines & Immunotherapeutics, 2018
Cross-talk by pattern recognition receptors may facilitate the maturation of dendritic cells and fine tune the immune response. Thus, the inclusion of ligands agonistic to multiple receptors in a vaccine formula may be an effective strategy to elicit ...
Cunbao Liu   +6 more
doaj   +1 more source

Tumor Microenvironment Multiple Responsive Nanoparticles for Targeted Delivery of Doxorubicin and CpG Against Triple-Negative Breast Cancer

open access: yesInternational Journal of Nanomedicine, 2022
Fenfen Gu,1,* Chuling Hu,2,* Wei Cao,3,* Chao Li,1 Qingming Xia,4 Yuan Gao,4 Yan Liu,1 Shen Gao1,4 1Department of Clinical Pharmacy, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, People’s Republic of
Gu F   +7 more
doaj  

Rhythm Pattern of Sole through Electrification of the Human Body When Walking

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2008
The rhythm of automatic cyclic movements such as walking is known to be generated by a rhythm generator called CPG in the spinal cord. The measurement of rhythm characteristics in walking is considered to be important for analyzing human bipedal walking ...
Kiyoaki TAKIGUCHI   +2 more
doaj   +1 more source

Enxerto autógeno de crista ilíaca na reconstrução do processo alveolar em portadores de fissura labiopalatina: estudo de 30 casos

open access: yesRevista do Colégio Brasileiro de Cirurgiões
A reconstrução do processo alveolar em pacientes portadores de fissuras labiopalatais (FLP) é fundamental para erupção de dentes permanentes e para o restabelecimento estético através de implantes osteointegrados.
João Luiz Carlini   +4 more
doaj   +1 more source

TLR9-mediated activation of dendritic cells by CD32 targeting for the generation of highly immunostimulatory vaccines

open access: yesHuman Vaccines & Immunotherapeutics, 2019
The rational for designing dendritic cell (DC)-targeted immunotherapies is their central role in orchestrating immunity. Most studies addressing antigen-targeting to DCs for eliciting T cell responses have employed ex-vivo matured DCs derived from ...
J. A. Sepulveda-Toepfer   +7 more
doaj   +1 more source

Antigen-adjuvant interactions, stability, and immunogenicity profiles of a SARS-CoV-2 receptor-binding domain (RBD) antigen formulated with aluminum salt and CpG adjuvants

open access: yesHuman Vaccines & Immunotherapeutics, 2022
Low-cost, refrigerator-stable COVID-19 vaccines will facilitate global access and improve vaccine coverage in low- and middle-income countries. To this end, subunit-based approaches targeting the receptor-binding domain (RBD) of SARS-CoV-2 Spike protein ...
Sakshi Bajoria   +15 more
doaj   +1 more source

Organic Matter Burial in Deep-Sea Fans: A Depositional Process-Based Perspective

open access: yesJournal of Marine Science and Engineering, 2022
Organic matter burial in the deep-sea fan sediments is an important component of the long-term carbon cycle. Although there is increasing recognition of the importance of organic matter in deep-sea sediments, a major focus has been on mudstones, commonly
Arif Hussain, Khalid Al-Ramadan
doaj   +1 more source

Human non-CpG methylation patterns display both tissue-specific and inter-individual differences suggestive of underlying function

open access: yesEpigenetics, 2022
DNA methylation (DNAm) in mammals is mostly examined within the context of CpG dinucleotides. Non-CpG DNAm is also widespread across the human genome, but the functional relevance, tissue-specific disposition, and inter-individual variability has not ...
Philip Titcombe   +10 more
doaj   +1 more source

CpG-Based Nanovaccines for Cancer Immunotherapy

open access: yesInternational Journal of Nanomedicine, 2021
Wenqiang Chen,1 Mingxia Jiang,1 Wenjing Yu,1 Zhiwei Xu,1 Xinyue Liu,1 Qingmiao Jia,1 Xiuwen Guan,1– 3 Weifen Zhang1– 3 1College of Pharmacy, Weifang Medical University, Weifang, 261053, People’s Republic of China; 2Collaborative Innovation Center for ...
Chen W   +7 more
doaj  

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