Results 11 to 20 of about 196,785 (313)

In Vivo Control of CpG and Non-CpG DNA Methylation by DNA Methyltransferases [PDF]

PLoS Genetics, 2012
The enzymatic control of the setting and maintenance of symmetric and non-symmetric DNA methylation patterns in a particular genome context is not well understood. Here, we describe a comprehensive analysis of DNA methylation patterns generated by high resolution sequencing of hairpin-bisulfite amplicons of selected single copy genes and repetitive ...
Arand, Julia, Spieler, David, Karius, Tommy, Branco, Miguel R., Meilinger, Daniela, Meissner, Alexander, Jenuwein, Thomas, Xu, Guoliang, Leonhardt, Heinrich, Wolf, Verena, Walter, Jörn   +10 more
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THE PROBLEM OF GENDER VOTING IN THE WEIMAR REPUBLIC

RUDN Journal of World History, 2018
The article is devoted to the problem of gender vote in the Weimar republic: what were political preferences of the German women of that period, who only had acquired the right to vote under the new constitution.
Eduard E Shults
doaj   +1 more source

Valorization and biological effect of Zizuphus jujuba Mill. vegetable oil. [Valorisation et effet biologique de l'huile végétale des graines de Ziziphus jujuba Mill. ]

Nutrition & Santé, 2023
Introduction. The natural plant resources are products with high added value, used in various fields for the manufacture of a wide variety of products. Objective.
Razika LAOUFI, Khaled BOUDJEMA, Samia LEFKIR, Narimen BENHABYLES, Ouahiba BOUCHENAK, Karima YAHIAOUI   +5 more
doaj   +1 more source

Orphan CpG islands identify numerous conserved promoters in the mammalian genome [PDF]

, 2010
This work was funded by grants from the Wellcome Trust (077224; http://www.wellcome.ac.uk/) and the Medical Research Council (G0800026; http:// www.mrc.ac.uk/index.htm).CpG islands (CGIs) are vertebrate genomic landmarks that encompass the promoters of ...
Gruenewald-Schneider, Ulrike, Shaun Webb, Bird, A.P.; id_orcid, Webb, Shaun, Smith Colin, Kerr, A.R.W., Andrews, Robert, Keith D James, Daniel J. Turner, Turner, D.J., Webb, S., James, Keith D., James, K.D., Robert S Illingworth, Robert Andrews, Webb Shaun, Smith, Colin; id_orcid, Keith D. James, Harrison David J., David J. Harrison, Alastair R. W. Kerr, Bird, Adrian P., Gruenewald-Schneider, U., Gruenewald-Schneider Ulrike, Turner Daniel J., Andrews, R., Smith, Colin, Illingworth Robert S., Turner, Daniel J., Illingworth, Robert S., Ulrike Gruenewald-Schneider, David J Harrison, Bird Adrian P., Robert S. Illingworth, Alastair R W Kerr, Colin Smith, Andrews Robert, Kerr, Alastair R. W., Illingworth, R.S., Kerr Alastair R. W., Harrison, D.J., Daniel J Turner, James Keith D., Adrian P. Bird, Harrison, David J., Adrian P Bird   +45 more
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The mutational spectrum of non-CpG DNA varies with CpG content [PDF]

Genome Research, 2010
The accumulation of base substitutions (mutations) not subject to natural selection is the neutral mutation rate. Because this rate reflects the in vivo processes involved in maintaining the integrity of genetic information, the factors that affect the neutral mutation rate are of considerable interest.
Walser, Jean-Claude, Furano, Anthony V.
openaire   +2 more sources

RNA virus attenuation by codon pair deoptimisation is an artefact of increases in CpG/UpA dinucleotide frequencies [PDF]

, 2014
Mutating RNA virus genomes to alter codon pair (CP) frequencies and reduce translation efficiency has been advocated as a method to generate safe, attenuated virus vaccines.
David J Evans, Fiona Tulloch, Evans, David John, Tulloch, F., Ryan, M. D., Atkinson, N. J., Ryan, Martin D., Tulloch, Fiona, Martin D Ryan, Simmonds, Peter, Nicky J Atkinson, Atkinson, Nicky J., Peter Simmonds, Evans, David J., Simmonds, P., Evans, D. J.   +15 more
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The Basis of Anticancer Immunity Mechanism Induced by In Situ Vaccination [PDF]

Журнал Сибирского федерального университета: Серия Биология, 2020
The present review is an attempt to characterize the principles of both onset and development of the systemic antitumor immune response triggered by in situ vaccination, which is a new trend in anticancer immunotherapy.
Anastasia S. Proskurina, Vera S. Ruzanova, Tamara V. Tyrinova, Dmitry N. Strunkin, Svetlana S. Kirikovich, Genrikh S. Ritter, Yaroslav R. Efremov, Sergey S. Bogachev   +7 more
doaj   +1 more source

Factors to preserve CpG-rich sequences in methylated CpG islands [PDF]

BMC Genomics, 2015
Mammalian CpG islands (CGIs) normally escape DNA methylation in all adult tissues and developmental stages. However, in our previous study we unexpectedly identified many methylated CGIs in human peripheral blood leukocytes. Methylated CpG dinucleotides convert to TpG dinucleotides through deaminization of their cytosine bases more frequently than ...
Miyahara, Hiroki, Hirose, Osamu, Satou, Kenji, Yamada, Yoichi   +3 more
openaire   +2 more sources

Adaptive CPG Based Coordinated Control of Healthy and Robotic Lower Limb Movements [PDF]

, 2009
This paper proposes an adaptive CPG based controller for a lower limb prosthesis consisting of online trajectory generation and interlimb coordination. The adaptive CPG can produce multidimensional rhythmic patterns and modulate their frequency by tuning
Chong, Nak Young, You, Bum Jae, Jae-Kwan Ryu, Bum Jae You, Ryu, Jae-Kwan, Christensen, Henrik, Nak Young Chong, Henrik Christensen   +7 more
core   +1 more source

CpG underrepresentation and the bacterial CpG-specific DNA methyltransferase M.MpeI [PDF]

Proceedings of the National Academy of Sciences, 2012
Cytosine methylation promotes deamination. In eukaryotes, CpG methylation is thought to account for CpG underrepresentation. Whether scarcity of CpGs in prokaryotic genomes is diagnostic for methylation is not clear. Here, we report that Mycoplasms tend to be CpG depleted and to harbor a family of constitutively expressed or phase variable
Marek, Wojciechowski, Honorata, Czapinska, Matthias, Bochtler   +2 more
openaire   +2 more sources