Results 141 to 150 of about 3,829,242 (325)

Whole‐Genome Sequencing Pilot of the Central Asian Genomic Diversity Project Reveals Distinct Histories, Adaptation, and Introgression

Advanced Science, EarlyView.
As a pilot phase of the Central Asian Genomic Diversity Project, whole‐genome sequencing of 166 individuals from 20 Central Asian and Afghan Hazara populations reveals fine‐scale substructure shaped by repeated trans‐Eurasian migration and admixture. Integrated analyses uncover post‐admixture adaptation, archaic introgression, and medically relevant ...
Mengge Wang, Shuhan Duan, Qiuxia Sun, Renkuan Tang, Lintao Luo, Jie Zhong, Zhaxylyk Sabitov, CAGDP Consortium†, Lan‐Hai Wei, Chao Liu, Maxat Zhabagin, Guanglin He   +11 more
wiley   +1 more source

Decrease of Event Related Delta Oscillations in Euthymic Patients with Bipolar Disorder [PDF]

, 2013
68th Annual Scientific Meeting of the Society-of-Biological-Psychiatry -- MAY 16-18, 2013 -- San Francisco, CA[No Abstract Available]Soc Biol ...
Başar, Erol, Atagün, Murat İlhan, Masali, Belinda, Guntekin, Bahar, Tulay, Elif   +4 more
core  

Challenges and Future Prospects of Precision Medicine in Psychiatry

Pharmacogenomics and Personalized Medicine, 2020
Mirko Manchia,1– 3,* Claudia Pisanu,4,* Alessio Squassina,4,5 Bernardo Carpiniello1,2 1Section of Psychiatry, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy; 2Unit of Clinical Psychiatry, University ...
Manchia M, Pisanu C, Squassina A, Carpiniello B   +3 more
doaj  

Small animal imaging presents an opportunity for improving translational research in biological psychiatry. [PDF]

J Psychiatry Neurosci, 2021
Chakravarty MM, Guma E.
europepmc   +1 more source

Multiscale Circuit Architecture Associated With Memory Dysfunction in Temporal Lobe Epilepsy

Advanced Science, EarlyView.
A multiscale precision‐mapping framework reveals that memory impairment in temporal lobe epilepsy arises from the convergence of focal medial temporal pathology, strategic white matter disconnection, and limbic‐centered metabolic network dysfunction.
Jiajie Mo, Qiwen Yuan, Pengfei Zhang, Lin Sang, Zhong Zheng, Baotian Zhao, Xiu Wang, Chao Zhang, Wenhan Hu, Xiaoqiu Shao, Jianguo Zhang, Ruijin Yang, Kai Zhang   +12 more
wiley   +1 more source

Enabling Precision Psychiatry through 'omics': From Biomarkers to Biological Pathways [PDF]

, 2017
Enabling Precision Psychiatry through 'omics': From Biomarkers to Biological ...
Michael Berk (13060851), B Fernandes (13365966)   +1 more
core  

Mind-Brain Dualism in Psychiatry: Ethical Implications

Frontiers in Psychiatry, 2020
Walter Glannon
doaj   +1 more source

USING ELECTRONIC HEALTH RECORDS TO FACILITATE PRECISION PSYCHIATRY.

Biological Psychiatry
The use of clinical prediction models to produce individualised risk estimates can facilitate the implementation of precision psychiatry. As a source of data from large, clinically representative patient samples, electronic health records (EHRs) provide ...
Dominic Oliver, M. Arribas, B. Perry, Daniel Whiting, Graham Blackman, K. Krakowski, Aida Seyedsalehi, E. Osimo, S. Griffiths, Daniel Stahl, A. Cipriani, Seena Fazel, P. Fusar-Poli, Philip McGuire   +13 more
semanticscholar   +1 more source

Autoantigen mRNA‐LNP Vaccination Drives Therapeutic Efficacy in Preclinical Models for Autoimmunity

Advanced Science, EarlyView.
Systemic and intramuscular delivery of autoantigen mRNA via lipid nanoparticles reprograms antigen‐presenting cells toward a mature, homeostatic state, driving antigen‐specific T cell exhaustion and providing therapeutic efficacy across autoimmune disease models.
Paulien Baeten, Karen Beets, Tessa Schalley, Janne Verreycken, Gayel Duran, Daphne Lintsen, Lisa Schuetz, Xue Zhong, Rinke Nieuwschepen, Melissa Schepers, Brecht Moonen, Jeroen Bogie, Jana Van Broeckhoven, Carlo Heirman, Jurgen Van den Heuvel, Bart Vanderborght, Ismael Varela, Roxanne Nouille, Lotte Jacobs, Jessica Filtjens, Sabah Kasmi, Elise Seynaeve, Veronica Mavrovouna, Jana De Vrieze, Michael A. Brehm, Sandra Maréchal, Sophie Janssens, Florence Lambolez, Niels Hellings, Stefaan De Koker, Bieke Broux   +30 more
wiley   +1 more source

Grounding psychosis research: why observable signs should anchor biological investigations

Frontiers in Psychiatry
Biological psychiatry faces a significant epistemic challenge in identifying valid objects for mechanistic research. Both diagnostic constructs and individual symptoms are abstract symbols defined circularly within a closed hermeneutic system, creating a
Lena Palaniyappan, Lena Palaniyappan, Lena Palaniyappan   +2 more
doaj   +1 more source