Results 121 to 130 of about 3,178,330 (288)

Biological Psychiatry in Displaced Populations: What We Know, and What We Need to Begin to Learn. [PDF]

Biol Psychiatry Cogn Neurosci Neuroimaging, 2022
Javanbakht A, Grasser LR.
europepmc   +1 more source

Psychiatry

, 2017
Decades ago, the psychiatrist Leon Eisenberg observed that whereas the psychological theories that previously dominated psychiatry were “brainless” (i.e., lacking in grounding in neuroscience), the biological theories that followed them were “mindless ...
Joel Paris
core   +1 more source

The unbearable lightness of reductionist physicalism in contemporary psychiatry

, 2020
Being one of the most renowned subjects in philosophy, mind-body problem focuses on the relationship between physical and mental phenomena. Various approaches have been developed throughout history with two perspectives having been the most prominent ...
GÜRSOY, SÜHA CAN, SAYAR, MUSTAFA KEMAL
core   +1 more source

Brain Network Dynamics of Local and Global Predictive Processing in Aging

Advanced Science, EarlyView.
Separation of concurrent whole‐brain networks in source‐reconstructed magnetoencephalography (MEG) data suggests that healthy aging reorganizes, rather than uniformly attenuates, neural responses elicited from hierarchical auditory violations. Enhanced early sensory deviance processing alongside reduced higher‐order cognitive responses suggests a large‐
Mathias Houe Andersen, Gemma Fernández‐Rubio, David R. Quiroga‐Martinez, Mattia Rosso, Mathias Klarlund, Kit Melissa Larsen, Hartwig Roman Siebner, Morten L. Kringelbach, Peter Vuust, Leonardo Bonetti   +9 more
wiley   +1 more source

Biological psychiatry: time for new paradigms [Editorial Material]

Biological psychiatry has not yet produced clinically viable biomarkers for any of the major psychiatric diseases, and the past 25 years have not brought any fundamentally new biological treatment principles.
Linden, David
core   +1 more source

Cryo‐EM and NMR Reveal a Membrane‐Gated Doc2B–Munc13‐1 Complex and a Helical Doc2B‐SNARE‐Binding Interface

Advanced Science, EarlyView.
Biophysical studies of Doc2B yield a cryo‐electron microscopy structure of its complex with the synaptic vesicle priming factor Munc13‐1 and its binding site to the SNARE complex that mediates synaptic vesicle fusion. These and other results suggest a novel model whereby Doc2 proteins regulate neurotransmitter release through sequential interactions ...
Cyrus T. Rastegar, Julia Powell, Aleksandra Wosztyl, Guillaume David, Klaudia Jaczynska, Xiao‐chen Bai, Yan Han, Zhe Chen, Josep Rizo   +8 more
wiley   +1 more source

Grounding psychosis research: why observable signs should anchor biological investigations

Frontiers in Psychiatry
Biological psychiatry faces a significant epistemic challenge in identifying valid objects for mechanistic research. Both diagnostic constructs and individual symptoms are abstract symbols defined circularly within a closed hermeneutic system, creating a
Lena Palaniyappan, Lena Palaniyappan, Lena Palaniyappan   +2 more
doaj   +1 more source

The World Federation of Societies of Biological Psychiatry guidelines on the assessment and pharmacological treatment of compulsive sexual behaviour disorder. [PDF]

Dialogues Clin Neurosci, 2022
Turner D, Briken P, Grubbs J, Malandain L, Mestre-Bach G, Potenza MN, Thibaut F.   +6 more
europepmc   +1 more source

The casual relationship of endoplasmic reticulum stress and phosphorylation of Tau protein may reinforce progression of neurodegeneration leading to cognitive impairment and Alzheimer's Disease

, 2011
The 5th Annual Scientific Meeting of the Hong Kong Society of Biological Psychiatry, Hong Kong, 19-20 March ...
Wuwongse, S, Lau, CF, Zhang, Q, Ho, YS, Hung, HL, Yang, X, Chang, RCC   +6 more
core  

WFS1 Deficiency Impairs PIAS4‐Associated SUMOylation and Increases Ubiquitin‐Mediated Spermatogenesis‐Related Protein Degradation Leading to Testicular Male Infertility

Advanced Science, EarlyView.
The findings establish a critical role for WFS1 in human male fertility. Mechanistically, WFS1 interacts with PIAS4 to promote the SUMOylation of key spermatogenesis‐associated proteins, which in turn competitively inhibits their K48‐linked ubiquitin‐mediated degradation during spermatogenesis.
Yunchuan Tian, Guicheng Zhao, Xiang Wang, Xinyao Tang, Gan Shen, Tiechao Ruan, Chuan Jiang, Shikun Zhao, Jincheng Zhang, Xinyue Cui, Liangchai Zhuo, Jun Ma, Yihong Yang, Tingting Lin, Ying Shen   +14 more
wiley   +1 more source