Results 81 to 90 of about 309,058 (173)
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro+2 more
wiley +1 more source
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt+4 more
wiley +1 more source
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel+2 more
wiley +1 more source
An Annotated List of Disciplines and Sub-disciplines in the Biological Sciences [PDF]
openaire +1 more source
Molecular Paleontology has not been included in the syllabus of the discipline of Paleontology in undergraduate courses in Biological Sciences. However, if inserted in the discipline's Teaching Plan, Molecular Paleontology could bring future biologists closer to Paleobiology, a field of research that is practically unexplored in Brazil.
openaire +1 more source
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche+2 more
wiley +1 more source
What we can freeze from the body and why : a historical, physical, and mathematical introduction [abstract] [PDF]
This presentation was made during the session "After the Body: Is It Still Human?"Abstract of a presentation given at the 2008 Body Project conference at the University of Missouri-Columbia.The public often links cryobiology, the study of biological ...
Benson, James
core
Most MmpLs transport lipids and glycolipids of the complex mycomembrane of mycobacteria. This study shows that MmpL10 from Mycobacterium smegmatis, the transporter of the trehalose polyphosphate precursor, harbors a coiled‐coil‐like extension. Biochemical and electron microscopy studies demonstrate that the coiled‐coil enables MmpL10 to trimerize.
Julie Couston+7 more
wiley +1 more source
Feature analysis of multidisciplinary scientific collaboration patterns based on PNAS
The features of collaboration patterns are often considered to be different from discipline to discipline. Meanwhile, collaborating among disciplines is an obvious feature emerged in modern scientific research, which incubates several interdisciplines ...
Duan, Xiaojun+4 more
core +1 more source
Evolutionary interplay between viruses and R‐loops
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi+4 more
wiley +1 more source