Results 141 to 150 of about 1,815,049 (345)

InteractiVenn: a web-based tool for the analysis of sets through Venn diagrams

open access: yesBMC Bioinformatics, 2015
Set comparisons permeate a large number of data analysis workflows, in particular workflows in biological sciences. Venn diagrams are frequently employed for such analysis but current tools are limited.
Henry Heberle   +4 more
semanticscholar   +1 more source

The Relevance of Evolutionary Science For Economic Theory and Policy [PDF]

open access: yes
NSF’s “Dear Colleague Letter” reflects the widely perceived need to go beyond current economic theory in the formulation of public policy. At the same time, there is a profound lack of unity among the disciplines that comprise the behavioral, social, and
David Sloan Wilson, John M. Gowdy
core  

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

open access: yesFEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura   +8 more
wiley   +1 more source

Identification of Evidence-Based Biospecimen Quality-Control Tools

open access: yesThe Journal of Molecular Diagnostics, 2013
Control of biospecimen quality that is linked to processing is one of the goals of biospecimen science. Consensus is lacking, however, regarding optimal sample quality-control (QC) tools (ie, markers and assays). The aim of this review was to identify QC tools, both for fluid and solid-tissue samples, based on a comprehensive and critical literature ...
Betsou, Fotini   +10 more
openaire   +3 more sources

Educating the educators: Incorporating bioinformatics into biological science education in Malaysia [PDF]

open access: yes, 2012
Bioinformatics can be defined as a fusion of computational and biological sciences. The urgency to process and analyse the deluge of data created by proteomics and genomics studies has caused bioinformatics to gain prominence and importance. However, its
Hussein, Huszalina   +3 more
core  

Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1

open access: yesFEBS Letters, EarlyView.
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri   +5 more
wiley   +1 more source

Geneious Basic: An integrated and extendable desktop software platform for the organization and analysis of sequence data

open access: yesBioinform., 2012
Summary: The two main functions of bioinformatics are the organization and analysis of biological data using computational resources. Geneious Basic has been designed to be an easy-to-use and flexible desktop software application framework for the ...
Matthew D. Kearse   +13 more
semanticscholar   +1 more source

Protein kinase FAM20C—when subcellular localization matters

open access: yesFEBS Letters, EarlyView.
FAM20C is a Golgi‐resident kinase that phosphorylates proteins along the entire secretory pathway. The presence of potential FAM20C substrates in the cytoplasm or nucleus raises the question of how the kinase and its substrates encounter each other. Protein kinases achieve signaling specificity through consensus sequence recognition and subcellular ...
Francesca Noventa, Mauro Salvi
wiley   +1 more source

Promoting Critical Thinking in Biological Sciences in the Era of Artificial Intelligence: The Role of Higher Education

open access: yesTrends in Higher Education
The integration of artificial intelligence (AI) into the biological sciences marks a transformative era, reshaping research methodologies, data analysis, and hypothesis generation.
Christos Papaneophytou   +1 more
doaj   +1 more source

Práticas laboratoriais como ferramenta de ensino aprendizagem na disciplina de biologia celular, no curso de licenciatura em ciências biológicas / Laboratory practices as a tool for teaching and learning in cellular biology, in the bachelor's degree course in biological sciences [PDF]

open access: gold, 2021
Matheus Gomes da Costa   +7 more
openalex   +1 more source

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