Results 141 to 150 of about 16,651,738 (349)

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Biological invasions in West Africa: Introducing the Wan@bi Network as a multi-stakeholder science-society interface tool

ARPHA Conference Abstracts
Biological invasions represent a major global concern, intensifying major environmental and socio-economic challenges, including biodiversity loss, food insecurity, and risks to public health. In West Africa, however, the ecological and socio-economic impacts of biological invasions remain largely under-recognized by academic, policy, and socio ...
Diagne, Christophe, Dobigny, Gauthier, Ag Atteyine, Solimane, Badou, Sylvestre, Bal, Amadou Bocar, Brouat, Carine, Dalecky, Ambroise, Danzabarma, Aziz, Dossou, Henri-Joël, Etougbetche, Jonas, Granjon, Laurent, Hima, Karmadine, Houemenou, Gualbert, Kindomissi, Mahoutin, Sarr, Oumar Mal, Niare, Sirama, Toure, Mamour, Gauthier, Nathalie   +17 more
openaire   +1 more source

Biological Sciences Newsletter, Spring/Summer 2009

, 2009
This is the alumni newsletter for the Dept.

core  

The upper limit of protein thermostability [PDF]

, 1989
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Applied Biological Sciences, 1989.Includes bibliographical references (leaves 143-158).by David B.
Volkin, David B. (David Bernard)
core  

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Biological Sciences Newsletter, Fall/Winter 2016

, 2016
This is the alumni newsletter for the Dept.

core  

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Initial training of biological sciences teachers: living the interactive methodology as teaching tools

, 2010
The present paper, developed with a group of second period of Biology Degree, had as main objective analyze our experience in the utilization of interactive methodology as didactic tool. Questionnaires and interviews were used with students in the process of collecting data; besides participant observation.
Araújo, Monica Lopes Folena, de Oliveira, Maria Marly, de França, Tereza Luiza   +2 more
openaire   +1 more source

Biological Sciences Newsletter, Fall/Winter 2018

, 2018
This is the alumni newsletter for the Dept.

core  

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source