Results 191 to 200 of about 16,651,738 (349)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Studies on cell disruption and cell debris removal in downstream bioprocessing

open access: yes, 1989
Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Applied Biological Sciences, 1989.Includes bibliographical references (leaves 176-181).by Sergio A.
Sánchez-Ruiz, Sergio A
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Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Spectroscopy for the biological sciences / Gordon G. Hammes.

open access: yes, 2005
Companion v. to: Thermodynamics and kinetics for the biological sciences / Gordon G. Hammes. c2000.Includes bibliographical references and index.x, 172 p.
Hammes, Gordon G., 1934- 7613   +1 more
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Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Factors affecting the thrombin inhibiting activity of heparin when immobilised to hydrogels by covalent bonding

open access: yes, 1986
Thesis (Sc. D.)--Massachusetts Institute of Technology, Dept. of Applied Biological Sciences, 1986.MICROFICHE COPY AVAILABLE IN ARCHIVES AND SCIENCE.Bibliography: leaves 157-166.by Sew-Wah Tay.Sc ...
Tay, Sew Wah
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Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Unusual catalytic properties of horseradish peroxidase

open access: yes, 1986
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Applied Biological Sciences, 1986.MICROFICHE COPY AVAILABLE IN ARCHIVES AND SCIENCEBibliography: leaves 217-231.by Jonathan Seth Dordick.Ph ...
Dordick, Jonathan Seth
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Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Regulation of pituitary function by 1α,25-dihydroxyvitamin D₃

open access: yes, 1985
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Applied Biological Sciences, 1985.MICROFICHE COPY AVAILABLE IN ARCHIVES AND SCIENCE.Vita.Includes bibliographical references.by Stanley David Rose.Ph ...
Rose, Stanley David
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