Results 191 to 200 of about 16,494,787 (294)

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

DiffMethylTools: a toolbox for the detection, annotation, and visualization of differential methylation. [PDF]

Life Sci Alliance
Derbel H, Kinnear E, Wong JJ, Liu Q.
europepmc   +1 more source

Biological invasions in West Africa: Introducing the Wan@bi Network as a multi-stakeholder science-society interface tool

Biological invasions represent a major global concern, intensifying major environmental and socio-economic challenges, including biodiversity loss, food insecurity, and risks to public health. In West Africa, however, the ecological and socio-economic impacts of biological invasions remain largely under-recognized by academic, policy, and socio ...
Diagne, Christophe, Dobigny, Gauthier, Ag Atteyine, Solimane, Badou, Sylvestre, Bal, Amadou Bocar, Brouat, Carine, Dalecky, Ambroise, Danzabarma, Aziz, Dossou, Henri-Joël, Etougbetche, Jonas, Granjon, Laurent, Hima, Karmadine, Houemenou, Gualbert, Kindomissi, Mahoutin, Sarr, Oumar Mal, Niare, Sirama, Toure, Mamour, Gauthier, Nathalie   +17 more
openaire   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

The applicability of DNA methylation-based tools in a low-income, sub-Saharan African population: Malawi longitudinal study of families and health. [PDF]

iScience
Zhuang BC, Konwar C, Kohler IV, Purcell H, Kumwenda B, Katundu K, Zulu A, Dever K, Brewis HT, MacIsaac JL, McMillan CT, Kobor MS, Kohler HP.   +12 more
europepmc   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Epigenomics and Ayurgenomics: Molecular Analysis of Ayurvedic Prakriti in Personalized Healthcare. [PDF]

Cureus
Nampalliwar AR, Khandale SN, Singh P, Pradhan K, Patel HC, Sinha CP.   +5 more
europepmc   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

From AI anxiety to educational opportunity: equitable and practical uses of artificial intelligence in STEM education. [PDF]

J Microbiol Biol Educ
Espinosa-Hernández S, Rodríguez-Pérez ME, Ramírez-Flores CJ.   +2 more
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source