Results 171 to 180 of about 16,651,738 (349)
School of Biological Sciences News, 2018 [PDF]
Alumni newsletter of Illinois State University\u27s School of Biological Sciences.https://ir.library.illinoisstate.edu/anb/1004/thumbnail ...
School of Biological Sciences
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The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Mutational spectra of MNNG and ICR-191 in human cells
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept.
Cariello, Neal Foster
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Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
A recombinant DNA approach to the design and synthesis of novel polysaccharides
Thesis (Sc. D.)--Massachusetts Institute of Technology, Dept. of Applied Biological Sciences, 1988.Vita.Bibliography: leaves 119-125.by Donald Davidson Easson Jr.Sc ...
Easson, Donald Davidson, 1961-
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School of Biological Sciences News, 2014 [PDF]
Alumni newsletter of Illinois State University\u27s School of Biological Sciences.https://ir.library.illinoisstate.edu/anb/1000/thumbnail ...
School of Biological Sciences
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Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Applied Biological Sciences, 1987.Bibliography: leaves 125-134.by Matthew S.
Bryant, Matthew S. (Matthew Scott)
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School of Biological Sciences News, 2017 [PDF]
Alumni newsletter of Illinois State University\u27s School of Biological Sciences.https://ir.library.illinoisstate.edu/anb/1003/thumbnail ...
School of Biological Sciences
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