Results 101 to 110 of about 29,478,974 (394)

A stepwise emergence of evolution in the RNA world

FEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Stable States of Biological Organisms

, 2009
A novel model of biological organisms is advanced, treating an organism as a self-consistent system subject to a pathogen flux. The principal novelty of the model is that it describes not some parts, but a biological organism as a whole.
A. Lichtenberg, A. Perelson, D. Sornette, D. Sornette, E. P. Yukalova, G. Nicolis, I. Prigogine, J. P. Cobb, J.-Y. Henry, N. Bogolubov, R. Thom, V. I. Yukalov, V. Yukalov, V. Yukalov   +13 more
core   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

FEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp, Katharina Rataj, Stefanie König, Marcia E. Newcomer, Oliver Werz, Ulrike Garscha   +5 more
wiley   +1 more source

Multispectral, Thermal, and Hyperspectral Sensing Data Depict Stomatal Conductance in Grapevine

Remote Sensing
Climate-driven water challenges in the Pacific Northwest necessitate precise irrigation for sustainable vineyard management. In such scenarios, conservation of water using different approaches, including subsurface irrigation, becomes critical. Detecting
Kesevan Veloo, Carlos Zúñiga Espinoza, Alberto Espinoza Salgado, Pete W. Jacoby, Sindhuja Sankaran   +4 more
doaj   +1 more source

Ancient and methane-derived carbon subsidizes contemporary food webs

Nature Communications, 2016
Alluvial aquifers of river floodplains support abundant large-bodied consumers despite an absence of light and scarcity of organic carbon. DelVecchia et al.
Amanda G. DelVecchia, Jack A. Stanford, Xiaomei Xu   +2 more
doaj   +1 more source

Magnetic resonance microscopy and spectroscopy reveal kinetics of cryoprotectant permeation in a multicompartmental biological system.

Proceedings of the National Academy of Sciences of the United States of America, 1996
Successful cryopreservation of most multicompartmental biological systems has not been achieved. One prerequisite for success is quantitative information on cryoprotectant permeation into and amongst the compartments.
Mary Hagedorn, Edward W. Hsut, Ulrich PILATUSl, David E. Wildt, W. F. Rall, Stephen J. Blackbandii   +5 more
semanticscholar   +1 more source

Motion of Interfaces in Biological Systems

SSRN Electronic Journal, 2020
Interfaces might be characterised by properties such as energy per area, speed, width and interaction with inhomogeneities which may impede or accelerate their motion. We consider advancing tumour and apoptosis fronts as examples. We also consider boundaries which separate regions where cells cycles are synchronised from regions where they are ...
openaire   +2 more sources

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

FEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg, Laura De Cnop, Bernd Nidetzky   +2 more
wiley   +1 more source

bdbms -- A Database Management System for Biological Data

, 2006
Biologists are increasingly using databases for storing and managing their data. Biological databases typically consist of a mixture of raw data, metadata, sequences, annotations, and related data obtained from various sources.
Aref, Walid G., Eltabakh, Mohamed Y., Ouzzani, Mourad   +2 more
core   +2 more sources

COMPUTER SIMULATION AND COMPUTABILITY OF BIOLOGICAL SYSTEMS [PDF]

, 1986
The ability to simulate a biological organism by employing a computer is related to the ability of the computer to calculate the behavior of such a dynamical system, or the "computability" of the system.* However, the two questions of computability and ...
Baianu, Professor I.C., Lin, Ms. H.C.
core