Results 141 to 150 of about 29,478,974 (394)

Biological Diversity in the Patent System

open access: yesPLoS ONE, 2013
Biological diversity in the patent system is an enduring focus of controversy but empirical analysis of the presence of biodiversity in the patent system has been limited. To address this problem we text mined 11 million patent documents for 6 million Latin species names from the Global Names Index (GNI) established by the Global Biodiversity ...
Stephen Hall   +3 more
openaire   +5 more sources

Goodbye flat lymphoma biology

open access: yesFEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria   +3 more
wiley   +1 more source

THE EFFECTS OF RADIATIONS ON BIOLOGICAL SYSTEMS [PDF]

open access: bronze, 1935
Raymond G. Hussey, William R. Thompson
openalex   +1 more source

Simple model of self-organized biological evolution as completely integrable dissipative system

open access: yes, 1998
The Bak-Sneppen model of self-organized biological evolution of an infinite ecosystem of randomly interacting species is represented in terms of an infinite set of variables which can be considered as an analog to the set of integrals of motion of ...
H. Flyvbjerg   +9 more
core   +2 more sources

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1

open access: yesFEBS Letters, EarlyView.
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson   +7 more
wiley   +1 more source

A simple image intensifying system for Berg-Barrett topography [PDF]

open access: yes, 1975
A simple imaging system to facilitate crystal orientation with respect to the x−ray beam for Berg−Barrett topography has been constructed. This system consists of an image intensifier tube with an x−ray phosphor deposited on its fiber−optic input plate ...
Lau, S. S., Vreeland, T., Jr.
core  

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