Results 11 to 20 of about 5,744,468 (268)

Inflammatory Cytokines and Clinical Outcome Following Biological Therapy in Adult Bio-Naïve Psoriasis Patients [PDF]

Current Issues in Molecular Biology
Inflammatory cytokines may hold the key to the clinical evolution of psoriasis. The aims of this study are to find a correlation between levels of inflammatory cytokines such as TNF-α, IL-23, IL-17A, and IL-17F and disease duration and severity scores in
Teodora-Larisa Florian, Ioan-Alexandru Florian, Stefan Cristian Vesa, Lehel Beni, Meda Orăsan   +4 more
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Conventional and biological therapies in atopic dermatitis – a literature review

Journal of Education, Health and Sport, 2023
Introduction: Atopic dermatitis is a chronic, relapsing disease with a multifactoral etiology. The basic disorder of the atopic dermatitis is the disruption of the epidermal barrier.
Karolina Włodarczyk-Cybulska, Natalia Sergiel, Patrycja Maj, Piotr Mozer, Jakub Maternia, Michał Lazar, Agata Kania, Aleksandra Serwik-Trandasir, Malwina Gonet, Karolina Miszczyk   +9 more
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Fusions of Tumor-derived Endothelial Cells with Dendritic Cells Induces Antitumor Immunity

Scientific Reports, 2017
To explore dendritic cells/tumor-derived endothelial cells (DC/EC) fusion cells are potent stimulators of T cells to impact tumor progression. ECs were isolated from mice hepatoma cell line (H22) Xenograft, and dendritic cells were isolated from bone ...
Yingying Huang, Qiqi Mao, Jian He, Jing Su, Yi Peng, Wei Liang, Zixi Hu, Sufang Zhou, Xiaoling Lu, Yongxiang Zhao   +9 more
doaj   +1 more source

Efficient targeted tumor imaging and secreted endostatin gene delivery by anti-CD105 immunoliposomes

Journal of Experimental & Clinical Cancer Research, 2018
Background Anti-CD105 mAb-conjugated immunoliposomes, loaded with secreted mouse endostatin gene, were developed for targeted tumor imaging and antiangiogenic gene therapy.
Huiqin Zhuo, Baoshi Zheng, Jianming Liu, Yong Huang, Huiling Wang, Duo Zheng, Naiquan Mao, Jinyu Meng, Sufang Zhou, Liping Zhong, Yongxiang Zhao   +10 more
doaj   +1 more source

Aptamer-Functionalized Fluorescent Silica Nanoparticles for Highly Sensitive Detection of Leukemia Cells

Nanoscale Research Letters, 2016
A simple, highly sensitive method to detect leukemia cells has been developed based on aptamer-modified fluorescent silica nanoparticles (FSNPs). In this strategy, the amine-labeled Sgc8 aptamer was conjugated to carboxyl-modified FSNPs via amide ...
Juntao Tan, Nuo Yang, Zixi Hu, Jing Su, Jianhong Zhong, Yang Yang, Yating Yu, Jianmeng Zhu, Dabin Xue, Yingying Huang, Zongqiang Lai, Yong Huang, Xiaoling Lu, Yongxiang Zhao   +13 more
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Effects of NDUFA4 Overexpression on Growth of Human Colon Cancer Cells in vitro

Zhongliu Fangzhi Yanjiu, 2019
Objective To investigate the effects of NDUFA4 overexpression on the growth of human colon cancer cells in vitro and to explore its potential mechanism. Methods The recombinant plasmid p-NDUFA4 (p-NDUFA4) and the control plasmid (p-Cont) were transiently
LIU Shiming, DING Tao, LEI Liangyu, HU Lin, MAO Ling, CHEN Chao, GUO Mengmeng, XU Lin   +7 more
doaj   +1 more source

Infliximab tolerance in patients with rheumatoid arthritis in real clinical practice

Научно-практическая ревматология, 2020
A wide range of biological agents recently introduced into clinical rheumatology determines a special interest in their tolerance. The paper presents the authors’ own data, as well as a review of foreign literature on this issue.Objective: to analyze the
E. S. Aronova, G. V. Lukina, Ya. A. Sigidin   +2 more
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Leucopenia e trombocitopenia induzidas por etanercepte: relato de dois casos e revisão da literatura Leukopenia and thrombocytopenia induced by etanercept: two case reports and literature review

Revista Brasileira de Reumatologia, 2012
O fator de necrose tumoral alfa (TNF-alfa) é uma citocina pró-inflamatória, e seu excesso pode levar a sérias consequências. Esses efeitos são conhecidos por serem antagonizados por inibidores da atividade do TNF-alfa.
Valderílio Feijó Azevedo, Marília Barreto Gameiro Silva, Débora Karine Marinello, Felipe Dunin dos Santos, Guilherme Barreto Gameiro Silva   +4 more
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Pathogenic aspects of treatment of psoriatic patients

Vestnik Dermatologii i Venerologii, 2017
The article describes high incidence and morbidity rate of psoriasis, substantial reduction in the life quality and psychosocial disadaptation of patients, and presents certain particular features of psoriasis pathogenesis taking into consideration the ...
V. V. Chikin, L. F. Znamenskaya, A. A. Mineyeva   +2 more
doaj   +1 more source

Increasing the concentration of plasma molecules improves the biological activity of platelet-rich plasma for tissue regeneration

Scientific Reports
Platelet-rich plasma (PRP) has emerged as a promising therapy in a variety of medical fields. However, it is crucial to go beyond simple platelet concentration and examine the complex molecular composition both inside and outside platelets.
Mikel Sánchez, Jon Mercader Ruiz, Daniel Marijuán Pinel, Pello Sánchez, Nicolás Fiz, Jorge Guadilla, Juan Azofra, Maider Beitia, Diego Delgado   +8 more
doaj   +1 more source