Results 21 to 30 of about 1,154,039 (314)
Effects of Antisense Oligonucleotides Against miRNA-21 on Growth of Human Colon Cancer Cells in vivo
Zhongliu Fangzhi Yanjiu, 2019 Objective To investigate the effect of antisense oligonucleotides(ASOs) against miR-21 expression on the growth of human colon carcinoma cells line HCT116 in vivo.
LIU Shiming +5 more
doaj +1 more source
Conventional and biological therapies in atopic dermatitis – a literature review
Journal of Education, Health and Sport, 2023 Introduction: Atopic dermatitis is a chronic, relapsing disease with a multifactoral etiology. The basic disorder of the atopic dermatitis is the disruption of the epidermal barrier.
Karolina Włodarczyk-Cybulska +9 more
doaj +1 more source
Biologic Therapies for Severe Asthma
New England Journal of Medicine, 2022 Biologic Therapies for Severe Asthma Patients with severe asthma are at increased risk for a decreased quality of life, fixed airway obstruction, hospitalization, and death. Biologics may be required to reduce the disease burden. This review discusses the mechanisms, efficacy, and safety of biologics for severe asthma.
Guy G. Brusselle, Gerard H. Koppelman
openaire +3 more sources
Fusions of Tumor-derived Endothelial Cells with Dendritic Cells Induces Antitumor Immunity
Scientific Reports, 2017 To explore dendritic cells/tumor-derived endothelial cells (DC/EC) fusion cells are potent stimulators of T cells to impact tumor progression. ECs were isolated from mice hepatoma cell line (H22) Xenograft, and dendritic cells were isolated from bone ...
Yingying Huang +9 more
doaj +1 more source
Efficient targeted tumor imaging and secreted endostatin gene delivery by anti-CD105 immunoliposomes
Journal of Experimental & Clinical Cancer Research, 2018 Background Anti-CD105 mAb-conjugated immunoliposomes, loaded with secreted mouse endostatin gene, were developed for targeted tumor imaging and antiangiogenic gene therapy.
Huiqin Zhuo +10 more
doaj +1 more source
Nanoscale Research Letters, 2016 A simple, highly sensitive method to detect leukemia cells has been developed based on aptamer-modified fluorescent silica nanoparticles (FSNPs). In this strategy, the amine-labeled Sgc8 aptamer was conjugated to carboxyl-modified FSNPs via amide ...
Juntao Tan +13 more
doaj +1 more source
Challenges of biological therapy in patients with pustular psoriasis coexisting with psoriatic arthritis [PDF]
, 2017 Introduction . Psoriasis is a chronic inflammatory skin disease affecting approximately 2–3% of the general population. It is a condition with immunological and genetic background, coexisting with psoriatic arthritis in about 25% of cases. Biologic drugs
Joanna Narbutt +4 more
core +1 more source
Effects of NDUFA4 Overexpression on Growth of Human Colon Cancer Cells in vitro
Zhongliu Fangzhi Yanjiu, 2019 Objective To investigate the effects of NDUFA4 overexpression on the growth of human colon cancer cells in vitro and to explore its potential mechanism. Methods The recombinant plasmid p-NDUFA4 (p-NDUFA4) and the control plasmid (p-Cont) were transiently
LIU Shiming +7 more
doaj +1 more source
Biological Therapy for Asthma [PDF]
, 2021 Asthma is a heterogeneous chronic inflammatory disease in the respiratory tract that leads to recurrent episodic symptoms. Study about the mechanism of pathophysiology and immunology which stimulates chronic inflammation in asthma has been greatly ...
Meliana, Resti Yudhawati +1 more
core +1 more source
Infliximab tolerance in patients with rheumatoid arthritis in real clinical practice
Научно-практическая ревматология, 2020 A wide range of biological agents recently introduced into clinical rheumatology determines a special interest in their tolerance. The paper presents the authors’ own data, as well as a review of foreign literature on this issue.Objective: to analyze the
E. S. Aronova +2 more
doaj +1 more source