Results 21 to 30 of about 6,047,039 (310)

Efficient targeted tumor imaging and secreted endostatin gene delivery by anti-CD105 immunoliposomes

Journal of Experimental & Clinical Cancer Research, 2018
Background Anti-CD105 mAb-conjugated immunoliposomes, loaded with secreted mouse endostatin gene, were developed for targeted tumor imaging and antiangiogenic gene therapy.
Huiqin Zhuo, Baoshi Zheng, Jianming Liu, Yong Huang, Huiling Wang, Duo Zheng, Naiquan Mao, Jinyu Meng, Sufang Zhou, Liping Zhong, Yongxiang Zhao   +10 more
doaj   +1 more source

Effects of NDUFA4 Overexpression on Growth of Human Colon Cancer Cells in vitro

Zhongliu Fangzhi Yanjiu, 2019
Objective To investigate the effects of NDUFA4 overexpression on the growth of human colon cancer cells in vitro and to explore its potential mechanism. Methods The recombinant plasmid p-NDUFA4 (p-NDUFA4) and the control plasmid (p-Cont) were transiently
LIU Shiming, DING Tao, LEI Liangyu, HU Lin, MAO Ling, CHEN Chao, GUO Mengmeng, XU Lin   +7 more
doaj   +1 more source

Infliximab tolerance in patients with rheumatoid arthritis in real clinical practice

Научно-практическая ревматология, 2020
A wide range of biological agents recently introduced into clinical rheumatology determines a special interest in their tolerance. The paper presents the authors’ own data, as well as a review of foreign literature on this issue.Objective: to analyze the
E. S. Aronova, G. V. Lukina, Ya. A. Sigidin   +2 more
doaj   +1 more source

Biologic Therapies for Psoriasis

The Journal of Rheumatology Supplement, 2009
Psoriasis is a common chronic inflammatory skin disease that may lead to disability and significant effects on patients' quality of life. A challenge in psoriasis management is to use an effective therapy early in the disease course in order to achieve a safe and well tolerated maintenance of remission with an improvement of both skin and joint ...
de FELICE, C., ARDIGO, M., BERARDESCA, E.   +2 more
openaire   +3 more sources

Leucopenia e trombocitopenia induzidas por etanercepte: relato de dois casos e revisão da literatura Leukopenia and thrombocytopenia induced by etanercept: two case reports and literature review

Revista Brasileira de Reumatologia, 2012
O fator de necrose tumoral alfa (TNF-alfa) é uma citocina pró-inflamatória, e seu excesso pode levar a sérias consequências. Esses efeitos são conhecidos por serem antagonizados por inibidores da atividade do TNF-alfa.
Valderílio Feijó Azevedo, Marília Barreto Gameiro Silva, Débora Karine Marinello, Felipe Dunin dos Santos, Guilherme Barreto Gameiro Silva   +4 more
doaj   +1 more source

Increasing the concentration of plasma molecules improves the biological activity of platelet-rich plasma for tissue regeneration

Scientific Reports
Platelet-rich plasma (PRP) has emerged as a promising therapy in a variety of medical fields. However, it is crucial to go beyond simple platelet concentration and examine the complex molecular composition both inside and outside platelets.
Mikel Sánchez, Jon Mercader Ruiz, Daniel Marijuán Pinel, Pello Sánchez, Nicolás Fiz, Jorge Guadilla, Juan Azofra, Maider Beitia, Diego Delgado   +8 more
doaj   +1 more source

Pathogenic aspects of treatment of psoriatic patients

Vestnik Dermatologii i Venerologii, 2017
The article describes high incidence and morbidity rate of psoriasis, substantial reduction in the life quality and psychosocial disadaptation of patients, and presents certain particular features of psoriasis pathogenesis taking into consideration the ...
V. V. Chikin, L. F. Znamenskaya, A. A. Mineyeva   +2 more
doaj   +1 more source

Early Body Mass Index z‐Score Change and Resolution of Severe Malnutrition in Children With Sickle Cell Anemia in a Low‐Income Setting: A Prospective Single‐Arm Extension Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell anemia (SCA) in low‐income settings are at risk of severe malnutrition, but optimal nutritional management has not been established. We evaluated an intensified ready‐to‐use therapeutic food (RUTF) regimen in children with persistent severe malnutrition after initial treatment and assessed whether early ...
Safiya Gambo, Shehu Umar Abdullahi, Hassan Adam Murtala, Halima Kabir, Khadija A. Shamsu, Sari A. Acra, Virginia A. Stallings, Mark Rodeghier, Michael R. DeBaun, Lauren J. Klein   +9 more
wiley   +1 more source

Biological therapy of cancer [PDF]

Breast Cancer Research and Treatment, 1986
Interferons and monoclonal antibodies are among the most promising biological approaches to cancer treatment which have so far been investigated. Both natural and recombinant interferon-alpha preparations have shown activity in a number of trials in hematologic malignancies, even in previously treated patients; activity in solid tumors, however, has ...
openaire   +3 more sources

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine, Hallie Coltin, Sylvia Cheng, Lucie Lafay‐Cousin, Vanan Issai Magimairajan, Craig Erker, Stéphanie Vairy, Lynette Bowes, Adam Fleming, Donna Johnston, Sarah McKillop, Roona Sinha, Julie Bennett, Christina Coleman, Laura Wheaton, Shayna Zelcer, Samuele Renzi, Thai Hoa Tran   +17 more
wiley   +1 more source