Results 41 to 50 of about 1,154,039 (314)

Radiation protection and secondary cancer prevention using biological radioprotectors in radiotherapy

open access: yes, 2015
Radiotherapy is the feasible treatment approach for many malignant diseases and cancers. New radiotherapy techniques such as ion therapy, stereotactic radiosurgery and intensity modulated radiation therapy deliver higher low dose radiation to large ...
Abdollahi, Hamid; Department of Medical Physics, School of Medicine, Iran University of Medical Sciences, Tehran   +5 more
core   +1 more source

The ratio of nicotinic acid to nicotinamide as a microbial biomarker for assessing cell therapy product sterility

open access: yes, 2022
Controlling microbial risks in cell therapy products (CTPs) is important for product safety. Here, we identified the nicotinic acid (NA) to nicotinamide (NAM) ratio as a biomarker that detects a broad spectrum of microbial contaminants in cell cultures ...
Springs, Stacy L.   +7 more
core   +1 more source

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro   +11 more
wiley   +1 more source

Biologic Therapies for Psoriasis

open access: yesThe Journal of Rheumatology Supplement, 2009
Psoriasis is a common chronic inflammatory skin disease that may lead to disability and significant effects on patients' quality of life. A challenge in psoriasis management is to use an effective therapy early in the disease course in order to achieve a safe and well tolerated maintenance of remission with an improvement of both skin and joint ...
de FELICE, C.   +2 more
openaire   +3 more sources

Advanced biological therapy in colorectal cancer

open access: yes, 2023
colorectal cancer (CRC) is the third most common diagnosed and the second deadliest malignancy among men and women combined. CRC has both strong environmental-related and genetic risk factors. CRC encompasses a very heterogeneous group of diseases caused
Alqudah, Diya Abdulmuttalib Mohd
core  

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke   +4 more
wiley   +1 more source

Longitudinal Study of Cognitive Functioning in Adults with Juvenile Idiopathic Arthritis

open access: yesBiomedicines, 2022
Objective: To prospectively evaluate possible decline of cognitive functions in adult patients with juvenile idiopathic arthritis (JIA) and identify associated factors.
Natalia Mena-Vázquez   +13 more
doaj   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta   +6 more
wiley   +1 more source

Molecular Biomarkers in Perthes Disease: A Review

open access: yesDiagnostics, 2023
Background: Perthes disease is a juvenile form of osteonecrosis of the femoral head that affects children under the age of 15. One hundred years after its discovery, some light has been shed on its etiology and the biological factors relevant to its ...
Vesna Spasovski   +6 more
doaj   +1 more source

Affibody molecules : potential for in vivo imaging of molecular targets for cancer therapy

open access: yes, 2007
Targeting radionuclide imaging of tumor-associated antigens may help to select patients who will benefit from a particular biological therapy. Affibody molecules are a novel class of small (approximately 7 kDa) phage display-selected affinity proteins ...
Abrahmsén, Lars   +5 more
core   +1 more source

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